Wisepowder muaj tag nrho cov khoom siv ntawm cov khoom siv ntawm Aging & Antiaging, thiab muaj tag nrho cov kev tswj hwm zoo.

Qhia 1-8 ntawm 19 cov ntsiab lus

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Kev laus & Kuaj (Tiv thaiv kev laus)

Kev laus yog ib yam uas peb txhua tus ua tab sis nkag siab tsawg heev txog. Koj lub paj hlwb tau hloov pauv raws li koj lub hnub nyoog uas yuav muaj kev cuam tshuam me ntawm koj lub cim xeeb lossis kev txawj xav.Yog nws yooj yim los ua ib daim ntawv teev txhua yam kev hloov pauv uas tuaj nrog lub hnub nyoog - nco ploj, wrinkles, leeg poob.
Antiaging (los tiv thaiv kev laus) tuaj yeem yog lub ntsiab lus nyuaj rau kev daws teeb meem: kev tawm tsam tam sim no tau tawm tsam ntawm lub ntsiab lus ntawm lo lus hauv kev tshawb fawb thiab tshuaj, thiab raws li lub cim rau cov khoom lag luam hauv nquag thiab feem ntau dag ntxias.
Antiaging (Los tiv thaiv kev laus) tam sim no muaj ib tug xov tooj ntawm qhov txawv heev lub ntsiab lus thiab kev xav paub.
-Nyob hauv lub zej lub zos kev tshawb fawb los tiv thaiv kev laus (tshuaj tiv thaiv kev laus) tshawb xyuas tshwj xeeb yog ua rau qeeb qeeb, tiv thaiv lossis thim rov qab rau cov txheej txheem kev laus. Thaum lub neej tom ntej zoo li muaj kev cia siab, tam sim no tsis muaj pov thawj thiab muaj kev kho mob thev naus laus zis uas qeeb los yog thim rov qab kev laus hauv tib neeg.
-Txoj hauv kev kho mob thiab ua lag luam hauv zej zog, tshuaj tiv thaiv kev laus txhais tau tias ntxov paub, tiv thaiv thiab kho kab mob ntsig txog lub hnub nyoog Qhov no txawv heev ntawm kev qhia txog cov txheej txheem kev laus dhau ntawm nws tus kheej, thiab ntau cov tswv yim thiab cov kev kho muaj nyob rau tam sim no. Piv txwv li Alzheimer txoj kev kho mob, kab mob uas cuam tshuam rau kev laus.
-Cov hauv kev lag luam dav dav - uas suav nrog ntau qhov kev dag ntxias lossis cov lag luam tsis zoo - kev tiv thaiv kev laus yog qhov muaj txiaj ntsig zoo thiab cov qauv siv los ua kom muag khoom.

Antiaging hmoov daim ntawv thov

Nyob rau hauv cov ncauj ke no, los tiv thaiv cov khoom lag luam kev laus muaj ntau zuj zus. Antiaging hmoov daim ntawv thov muaj xws li:
-Qhov khoom siv tu cev
-Nyob tsis zoo cov khoom siv kho mob
-Tus dej haus ua ke
-Txoj khoom lag luam
Laus & Alzheimer txoj kev kho mob
Dementia muaj ntau yam nrog lub hnub nyoog.Qhov 3% ntawm cov neeg muaj hnub nyoog 65 thiab 74, 19% ntawm 75 thiab 84, thiab ze li ib nrab ntawm cov neeg hnub nyoog 85 xyoo muaj dementia.Qhov spectrum ntau yam los ntawm qhov tsis paub tab mus rau neurodegenerative kab mob ntawm Alzheimer tus kab mob, kab mob cerebrovascular, Parkinson tus kab mob thiab Lou Gehrig's kab mob.
Kev laus yog qhov pheej hmoo txaus ntshai rau Alzheimer tus kab mob. Alzheimer yog ib hom kev dementia uas ua rau muaj teeb meem nrog nco, xav thiab tus cwj pwm. Alzheimer cov tsos mob feem ntau yuav maj mam dhau los thiab cuam tshuam rau lub sijhawm, ua rau hnyav txaus uas cuam tshuam nrog kev ua haujlwm txhua hnub. "Peb paub tias hnub nyoog tsuas yog qhov txiaj ntsig zoo tshaj plaws rau Alzheimer, yog li nws tsis yog qhov xav tsis thoob uas peb pom lub hom phiaj tshuaj uas tseem cuam tshuam rau kev laus,"
FDA kuj tau pom zoo xws li Namzaric, kev sib xyaw ua ke ntawm Namenda (memantine) thiab Aricept, rau kev kho mob los ntawm kev muaj mob me mus rau mob hnyav Alzheimer.
Namendais (memantine) ntseeg ua haujlwm los ntawm kev tswj hwm glutamate, ib qho tseem ceeb ntawm cov tshuaj lom neeg lub hlwb. Thaum tsim nyob rau hauv ntau dhau heev lawm, glutamate yuav ua rau lub hlwb tuag ntawm tes. Vim tias NMDA antagonists ua haujlwm sib txawv los ntawm cholinesterase inhibitors, ob hom tshuaj muaj peev xwm ua haujlwm nyob hauv kev sib xyaw.
Ntau cov khoom siv tshiab tau paub tias muaj txiaj ntsig zoo hauv kev kho Alzheimer tus kab mob. Xws li J-147 hmoov, CMS121 hmoov.

Antiaging hmoov khoom

J-147 hmoov (1146963-51-0): J147 yog ib yam dab tsi ntawm elixir niaj hnub ntawm lub neej, nws tau qhia txog kev kho mob Alzheimer thiab thim rov qab kev laus hauv cov nas thiab yuav luag npaj rau kev soj ntsuam hauv tib neeg.Lub pab pawg twb tau ua cov kev tshawb fawb ntxiv txog cov molecules uas tau hloov los ntawm J147 cov nyhuv rau mitochondrial ATP synthase - uas lawv tus kheej tuaj yeem yog cov hom phiaj tshuaj tshiab. J147 tau ua tiav FDA-yuav tsum tshuaj lom toxicology kuaj hauv cov tsiaj.
Alpha-lipoic acid hmoov (1077-28-7): Alpha-lipoic acid yog cov tshuaj zoo li vitamin hu ua antioxidant, uas txhais tau tias nws yuav muab kev tiv thaiv rau lub hlwb hauv kev puas tsuaj lossis raug mob.
Alpha-lipoic acid zoo li yuav pab tiv thaiv qee yam kev puas tsuaj ntawm tes hauv lub cev, thiab tseem rov qab qib vitamin xws li vitamin E thiab vitamin C. Tseem muaj pov thawj tias alpha-lipoic acid tuaj yeem txhim kho kev ua haujlwm thiab kev ua tiav ntawm cov neurons hauv ntshav qab zib.
Lub cim xeeb poob yog qhov kev txhawj xeeb ntawm cov laus dua.Nws ntseeg tias kev puas tsuaj los ntawm oxidative kev nyuaj siab ua lub luag haujlwm tseem ceeb hauv kev nco.
Vim tias alpha-lipoic acid yog qhov muaj zog txaus los tiv thaiv, kev tshawb fawb tau soj ntsuam nws lub peev xwm los ua kom qeeb qhov kev vam meej ntawm cov kev puas tsuaj los ntawm qhov cim xeeb ploj, xws li Alzheimer tus kab mob.
Poov xab, nplooj siab, raum, spinach, zaub cob pob, thiab qos yaj ywm yog qhov zoo ntawm alpha-lipoic acid.
CMS121 hmoov (1353224-53-9): Geroprotectors yog cov tshuaj uas muaj peev xwm ua kom qeeb ntawm tus tsiaj uas muaj hnub nyoog los ntawm kev tsom mus rau cov txheej txheem kev laus. Txoj kev kawm tshiab tshuaj xyuas ntau lub tebchaw thiab txheeb xyuas qee qhov tiv thaiv cov neurons los ntawm kev phom sij los ntawm kev ua qeeb qeeb ntawm kev laus; cov kws tshawb nrhiav cov npe tshuaj tiv thaiv no geroneuroprotectors.
Los ntawm kev siv cov tebchaw no ua cov hauv paus, cov kws tshawb nrhiav tau tsim peb tus neeg mob Alzheimer cov neeg sib tw hu ua CMS121, CAD31, thiab J147; lawv kuj siv fisetin thiab curcumin ncaj qha. Pab pawg neeg pom tau hais tias txhua tsib ntawm cov tebchaw txo qis biomarkers ntawm kev laus, ua rau muaj hnub nyoog nruab nrab ntawm cov nas thiab yoov, thiab txo cov cim dementia.

Muaj tshwm sim ntawm kev laus

Kev laus yog qhov cuam tshuam ntawm lub sijhawm ntawm tib neeg lub cev, thiab nws tshwm sim rau ntau theem:
-Cellular laus. Cov hnub nyoog ntawm tes nce raws pes tsawg zaus uas lawv tau rov ua dua. Lub xovtooj ntawm muaj peev xwm theej tau txog 50 lub sijhawm ua ntej cov khoom siv caj ces tsis tuaj yeem theej tawm tau raug lawm, uas yog vim muaj lub xov tooj luv. Kev puas tsuaj ntau rau cov cell los ntawm cov dawb radicals thiab lwm yam, ntau lub hlwb yuav tsum rov ua dua tshiab.
-Txoj kev laus. Cov tshuaj hormones yog qhov zoo tshaj rau cov laus, tshwj xeeb tshaj yog thaum me nyuam loj hlob thiab tiav hluas. Cov qib ntshav nce mus ib txhis. Puberty nqa pob txuv thiab qhov hws loj. Raws li peb tau laus dua, cov kev hloov pauv hloov ua rau cov tawv nqaij qhuav thiab lawm.
-Cov khoom puas tsuaj. Sau cov khoom puas yog sab nraud. Raug rau cov co toxins, lub hnub, khoom noj uas tsim kev puas tsuaj, kev ua qias tuaj, thiab pa taws ua rau lub cev raug mob. Sij hawm dhau mus, cov xwm txheej sab nraud tuaj yeem ua rau cov ntaub so ntswg puas tsuaj thiab lub cev ntog hauv qab nws lub peev xwm los tswj thiab kho cov hlwb, cov nqaij, thiab kabmob.
-Tus neeg laus txoj kev laus. Thaum koj mus txog koj lub hnub, koj lub hlwb ib txwm hloov khoom noj mus ua lub zog, uas tsim cov khoom lag luam tsim tawm uas tuaj yeem tsim kev puas tsuaj. Cov txheej txheem ntawm lub cev ua kom muaj zog thiab tsim kom muaj lub zog ua rau lub cev puas tsuaj dhau sijhawm. Qee tus neeg ntseeg tias kev ua qeeb qeeb ntawm cov khoom noj hauv lub cev los ntawm kev coj ua xws li kev txwv calorie yuav ua rau tib neeg lub cev qeeb qeeb.
Cov tsos mob tshwm sim ntawm Alzheimer muaj xws li kev pw tsis tsaug zog, taug kev, ntxhov siab, ntxhov siab, ntxhov siab, nyob tsis tswm, thiab kev nyuaj siab. Cov kws tshawb fawb tab tom kawm paub vim li cas cov tsos mob no tshwm sim thiab tab tom kawm kev kho mob tshiab - siv tshuaj thiab yeeb tshuaj - tswj lawv.

reference:

  1. Mortimer RK, Johnston JR (1959). “Lub neej ntawm tus kheej cov hlwb poov xab”. Xwm. 183 (4677): 1751–1752. Bibcode: 1959Natur.183.1751M. doi: 10.1038 / 1831751a0. hdl: 2027 / mdp.39015078535278. PMID 13666896
  2. Kev sim tshuaj tsom rau Alzheimer tus kab mob qhia pom cov kev ua los tiv thaiv kev laus "(Xov xwm tshaj tawm). Salk Lub Koom Haum. 12 Kaum Ib Hlis 2015. Retrieved November 13, 2015.
  3. Cov kws tshawb nrhiav txheeb xyuas lub hom phiaj molecular ntawm J147, uas tab tom ze kev kuaj mob los kho Alzheimer tus kab mob ". Kwv txhiaj 2018-01-30.
  4. Correlation ntawm Alzheimer Tus Kab Mob Neuropathologic Hloov Nrog Tus Paub Txog: Kev tshuaj xyuas ntawm Cov Ntawv Sau Ntawv Peter T. Nelson, Irina Alafuzoff, Eileen H. Bigio, Constantin Bouras, Heiko Braak, Nigel J. Cairns, Rudolph J. Castellani, Barbara J. Crain, Peter Davies, Kelly Del Tredici, Charles Duyckaerts, Matthew P. Frosch, Vahram Haroutunian, Patrick R. Hof, Christine M. Hulette, Bradley T. Hyman, Takeshi Iwatsubo, Kurt A. Jellinger, Gregory A. Jicha, Enikö Kövari, Walter A . Kukull, James B. Leverenz, Seth Hlub, Ian R. Mackenzie, David M. Mann, Eliezer Masliah, Ann C. McKee, Thomas J. Montine, John C. Morris, Julie A. Schneider, Joshua A. Sonnen, Dietmar R. Thal, John Q. Trojanowski, Juan C. Troncoso, Thomas Wisniewski, Randall L. Woltjer, Thomas G. Beach J Neuropathol Exp Neurol. Tus sau phau ntawv sau; muaj nyob hauv PMC 2013 Lub Ib Hlis 30. Luam tawm nyob rau hauv tsab ntawv kho kawg raws li: J Neuropathol Exp Neurol. 2012 Tsib Hlis; 71 (5): 362–381. doi: 10.1097 / NEN.0b013e31825018f7