cov khoom siv

Hydroxypinacolone Retinoate hmoov

Hydroxypinacolone retinoate (luv luv li HPR), tseem hu ua granactive retinoid, yog oxidized derivative ntawm retinol, uas tuaj yeem khi ncaj qha rau retinoic acid receptors (RARs). Nws muaj cov haujlwm ua haujlwm ntawm kev tswj cov metabolism hauv cov kabmob epidermal thiab stratum corneum. Nws tuaj yeem txo qhov sebum txeej, ua kom pom cov xim tawv nqaij, tiv thaiv kev laus ntawm daim tawv nqaij, Tiv thaiv pob txuv, ntxuav hniav dawb, thiab lwm yam. Tam sim no, nws yog tsuas yog siv rau kev tiv thaiv kev laus thiab tiv thaiv kom tsis txhob mob tshwm sim.

Wisepowder muaj peev xwm tsim tau thiab muab khoom ntau. Txhua qhov kev tsim khoom raws li cGMP thiab kev tswj hwm nruj, tag nrho cov ntaub ntawv xeem thiab cov qauv muaj.
Qeb:

Hydroxypinacolone Retinoate (HPR) hmoov Cov Lus Qhia

lub npe Hydroxypinacolone Retinoate hmoov
CAS 893412-73-2
purity 98%
Tshuaj lub npe Hydroxypinacolone Retinoate
Synonyms Rog-Soluble HPR; Dej-Soluble HPR; Hydroxypinacolone Retinoate; Hydroxypinacolone Retinoate, HPR; Hydroxyl pinacone retinoate Liposome; Liposomal Hydroxypinacolone Retinoate; Retinoic acid
molecular Formula C26H38O3
molecular Nyhav 398.58
Boling Point 508.5 ± 33.0 ° C (Xav Tau)
InChI Qhov Tseem Ceeb XLPLFRLIWKRQFT-XUJYDZMUSA-N
daim ntawv Khoom
tsos Cov hmoov daj lossis siv lead ua
Ib Sim Neej /
solubility insoluble hauv dej, thiab yooj yim hydrolyzed nyob rau hauv muaj zog acid thiab alkali
cia mob Khaws rau hauv lub tsev tso khoom txias, tso pa tawm. Qhov chaw cia khoom txias yuav tsum tsis pub tshaj 37 ° C. Nws yuav tsum tso nws kom sib xyaw los ntawm oxidants thiab tshuaj tua tau, thiab zam kev ntim khoom sib xyaw.
Daim ntawv thov Siv los ua tshuaj tiv thaiv kab mob.

Siv ua lub txias txias, tiv thaiv cov kab mob tawv tawv thiab lwm yam hauv cov khoom lag luam saib xyuas tus kheej.

Kuaj Cov Ntaub Ntawv Qhov

 

Hydroxypinacolone Retinoate hmoov 893412-73-2 General hauj lwm

Hydroxypinacolone retinoate muaj mob me dua thiab tsis haum dua li retinol thiab tuaj yeem siv cov khoom tu tawv nqaij kom zoo. Hydroxypinacolone retinoate muaj lub cev hnyav dua lub hnub nyoog dua li retinol, yog li ntawd daim tawv nqaij yuav nqus nws tsawg dua, thiab nws yuav siv sijhawm ntev kom ua rau daim tawv nqaij. Hydroxypinacolone retinoate kuj tsim nyog rau kho pob txuv, thaum nws tuaj yeem kho tus mob ntshav qab zib. Hydroxypinacolone retinoate sib txawv los ntawm lwm cov kua qaub retinoic acid (retinoic acid) derivatives. Nws tsis tas yuav hloov dua siab tshiab kom ua ncaj qha. Piv nrog retinoic acid, nws txoj kev ua pa yog qhov txo ntau. Nws muaj kev nyab xeeb dua los siv thoob plaws lub qhov muag, thiab tus nqi transdermal tseem zoo dua. Nws yog qhov ruaj khov dua li lwm cov sib txuas retinoic acid. Hydroxypinacolone retinoate muaj qhov me me ntawm qhov tsawg dua 100nm, uas tuaj yeem cuam tshuam cov khoom tseem ceeb hauv cov mis, thiab tib lub sijhawm, nws tuaj yeem nkag mus rau ntawm daim tawv nqaij kom ua hauj lwm zoo thiab tswj tau qhov tso tawm ntawm cov khoom tseem ceeb.

 

Hydroxypinacolone Retinoate hmoov 893412-73-2 Mechanism Of Action

Hydroxypinacolone retinoate txhawb kev nthuav dav thiab rov ua dua tshiab ntawm daim tawv nqaij, rov qab ua kom tawv nqaij tawv dua qub uas tau ua kom nyias nyias nrog cov hnub nyoog, ua tiav cov kab zoo thiab cov tawv nqaij nyob rau ntawm daim tawv nqaij, thaum tiv thaiv cov tawv nqaij los ntawm kev puas tsuaj ntxiv los ntawm wrinkles, thiab rov qab tawv nqaij kom zoo thiab elasticity, ua rau daim tawv nqaij mos thiab hluas.

Ib qho tseem ceeb ntawm Hydroxypinacolone retinoate dhau retinol thiab lwm cov vitamin A neeg siv tam sim no siv dav hauv cov tshuaj pleev ib ce yog tias nws tsis tas yuav hloov mus rau retinoic acid los sau cov kab zoo, ua kom pom pob, thiab tiv thaiv daim tawv. Thaum koj thov nws rau ntawm daim tawv nqaij, nws tuaj yeem khi ncaj qha rau cov chaw txais tshuaj thiab pib ua haujlwm, yog li cov kab mob epidermal ntawm daim tawv nqaij pib nthuav dav, sau cov kab ua kom zoo, thiab qee kom qhov qub wrinkles thiab txo cov pigmentation, txhim kho koj lub cev tawv nqaij, ua kom cov tawv nqaij saib ntau dua, ci, txawv, elastic, koj yuav saib yau dua.

Qhov txiaj ntsig tseem ceeb thib ob ntawm Hydroxypinacolone retinoate yog nws cov lus muaj nyob ruaj khov. Kev ntsuam xyuas cua sov tau qhia tias nws tuaj yeem ua haujlwm zoo rau daim tawv nqaij kom ntev txog 15h.

 

Hydroxypinacolone Retinoate hmoov 893412-73-2 Daim ntawv thov

Retinol derivative, uas muaj lub luag haujlwm ntawm kev tswj cov metabolism hauv ntawm daim tawv nqaij thiab stratum corneum cov, tuaj yeem tiv taus kev laus, tuaj yeem txo qis sebum, dilute epidermal pigments, ua lub luag haujlwm tiv thaiv daim tawv nqaij laus, tiv thaiv pob txuv, ua kom dawb thiab lub teeb me me. Thaum ua kom ntseeg tau tias muaj txiaj ntsig zoo ntawm retinol, nws kuj tseem txo nws qhov kev khaus. Tam sim no nws tau siv los tiv thaiv kev laus thiab tiv thaiv pob txuv rov tshwm sim.

 

Hydroxypinacolone Retinoate hmoov 893412-73-2 Tshawb nrhiav ntxiv

Hydroxypinacolone Retinoate hmoov siv tau Cov khoom lag luam

Cov khoom tiv thaiv kev laus: Txhawb nqa collagen synthesis hauv daim tawv nqaij, tiv thaiv collagen los ntawm kev puas tsuaj sai sai, thiab txhim kho cov kab zoo tuaj yeem pom hauv ib lub lis piam.

Cov khoom ua kom dawb: Txwv tsis pub tyrosinase, txhawb cov metabolism, thiab ua kom cov melanin ploj mus. Cov ntaub ntawv qhia pom tias kev sib xyaw nrog VC kuj tseem muaj txiaj ntsig zoo hauv kev kho pob txuv ntawm daim tawv nqaij.

Pob txuv khoom: Tsis tsuas yog tuaj yeem txo cov ntxau, tab sis kuj txo cov roj zais cia thiab ua kom pom cov pigmentation sab hnub poob los ntawm pob txuv.

Cov tshuaj pleev thaiv hnub: thaiv qhov nce ntawm MMP kev ua los ntawm ultraviolet rays, tiv thaiv elastin thiab dermal collagen, thiab txhim kho wrinkles thiab cov kab zoo los ntawm ultraviolet rays.

Kho khoom: txhawb kev sib xyaw ntawm hyaluronic acid hauv lub cev, txo cov tawv nqaij TEWL, txhawb nqa kev ua haujlwm ntawm keratinocytes, ua kom tuab ntawm txheej txheej txheej, thiab ua rau txheej txheej tawv nqaij muaj zog.

 

reference

[1] Kev ua tau zoo thiab kev nyab xeeb ntawm kev kho mob 12-lub hlis nrog kev sib xyaw ntawm hydroxypinacolone retinoate thiab retinol glycospheres raws li kev kho kev kho mob hauv cov neeg mob ntxau tom qab qhov ncauj isotretinoin.Bettoli V, Zauli S, Borghi A, Toni G, Ricci M, Bertoldi AM, Virgili AG Ital Dermatol Lub ntsej muag zoo. 2017 Lub Ob Hlis; 152 (1): 13-17.

[2] Kev kho mob me rau mob ntxau nrog rau kev sib xyaw nrog hydroxypinacolone retinoate, retinol glycospheres thiab papain glycospheres.Veraldi S, Barbareschi M, Guanziroli E, Bettoli V, Minghetti S, Capitanio B, Sinagra JL, Sedona P, Schianchi RG Ital Dermatol. Xyoo 2015 Lub Plaub Hlis; 150 (2): 143-7.

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