cov khoom siv

Compound 7P hmoov (1890208-58-8)

Raw Sib xyaw 7P hmoov uas txhawb nqa neurite outgrowth ntawm keeb kwm neurons muab tau los ntawm hippocampus, cerebral cortex, thiab retina. nyob rau hauv tus qauv tsiaj ntawm optic cov leeg raug mob, Raw Compound 7P hmoov tau pom tias ua kom muaj kev loj hlob ntawm qhov sib txawv-43 cov txiv neej zoo, qhia tau tias nyob rau hauv vitro neurite outgrowth kev ua si ntawm Raw Compound 7P hmoov txhais ua kev txhawb nqa axon kev tsim dua tshiab hauv vivo.

Chaw Tsim Tshuaj: Batch Production
pob: 1KG / hnab, 25KG / nruas
Wisepowder muaj peev xwm tsim tau thiab muab khoom ntau. Txhua qhov kev tsim khoom raws li cGMP thiab kev tswj hwm nruj, tag nrho cov ntaub ntawv xeem thiab cov qauv muaj.

Sib xyaw 7P hmoov (1890208-58-8) video

 

Compound 7P hmoov Piav Cov Ntaub Ntawv

lub npe Compound 7P hmoov
CAS 1890208-58-8
purity 98%
Tshuaj lub npe 2-[(2-methoxyphenyl)[(4-methylphenyl)sulfonyl]amino]-N-(4-methoxy-3-pyridinyl)acetamide
Synonyms Compound 7P

CHEMBL3824120

molecular Formula C22H23N3O5S
molecular Nyhav 441.5 g / mol
Melting Point Kwv yees li 159 ℃
InChI Qhov Tseem Ceeb NAXWKPFXCOBXLE-UHFFFAOYSA-N
daim ntawv Khoom
tsos Dawb
Ib Sim Neej 1-2h
solubility Soluble hauv ethyl acetate, dichloromethan;

Soluble me ntsis hauv methanol; insoluble hauv

dej

cia mob hauv qhov chaw qhuav, tawm ntawm lub teeb.
Daim ntawv thov Compound 7p tau tsim los ua ib qho hauv cov khoom sib txuas nrog lub hom phiaj los txheeb xyuas dual-acting thromboxane receptor antagonist / synthase inhibitors.
Kuaj Cov Ntaub Ntawv Qhov

 

Compound 7P hmoov General Cov lus piav qhia

Raw Sib xyaw 7P hmoov uas txhawb nqa neurite outgrowth ntawm keeb kwm neurons muab tau los ntawm hippocampus, cerebral cortex, thiab retina.

Hauv tus qauv tsiaj ntawm optic cov leeg raug mob, Raw Compound 7P tau pom tias ua rau muaj kev loj hlob ntawm qhov sib txawv-43 cov txiv neej zoo, qhia tau tias nyob rau hauv vitro neurite outgrowth kev ua si ntawm Raw Compound 7P txhais mus rau hauv kev txhawb nqa ntawm axon kev tsim dua tshiab hauv vivo.

 

Cheeb Tsam 7P (1890208-58-8) Keeb Kwm

Compound 7p tau tsim los ua ib qho hauv cov khoom sib txuas nrog lub hom phiaj los txheeb xyuas dual-acting thromboxane receptor antagonist / synthase inhibitors.

Qhov tseeb sib txuas 7p qhia tau xaiv rau prostaglandin I2 synthase (PTGIS, CYP8A1) tshaj li thromboxane synthase (CYP5A1).

 

Cheeb Tsam 7P (1890208-58-8) Kev Pab

  1. Rov saib cov roj seev cev lub taub hau
  2. Txhawb nqa neurite outgrowth ntawm keeb kwm kev coj neurons muab tau los ntawm hippocampus, cerebral cortex, thiab retina.

 

Compound 7P (1890208-58-8) Kev tshawb fawb ntau ntxiv

Ntxiv kev ua kom zoo ntawm cov sib txuas 7p thiab txhim kho cov txheej txheem los ntawm kev nws ua kom cov axon rov tsim dua tshiab hauv vivo yuav muab lub hauv paus rau kev txhim kho yav tom ntej los txhim kho cov tswv yim kho.

 

Compound 7P (1890208-58-8) Kev siv

  • Tsim, synthesis thiab cov molecular docking ntawm thiazolidinedione raws li benzene sulphonamide derivatives muaj pyrazole core ua cov neeg tuaj yeem tiv thaiv ntshav qab zib tau. Naim MJ, Alam O, Alam MJ, Hassan MQ, Siddiqui N, Naidu VGM, Alam MI. Bioorg Chem. 2018 Lub Ob Hlis; 76: 98-112. doi: 10.1016 / j.bioorg.2017.11.010. Epub 2017 Nov 16. PMID: 29169079
  • Phau ntawv tshiab 1,3,5-triazine derivatives muaj peev xwm tiv thaiv mob qog nqaij hlav ntau ntxiv los ntawm kev kho Bax, Bcl2 thiab Caspases qhia. Wang X, Yi Y, Lv Q, Zhang J, Wu K, Wu W, Zhang W. Chem Biol Drug Des. 2018 Mar; 91 (3): 728-734. doi: 10.1111 / cbdd.13133. Epub 2017 Nov 15. PMID: 29068538
  • Muaj peev xwm ua los tiv thaiv mob qog noj ntshav ntawm 7-O-pentyl quercetin: Ua kom zoo, daim nyias nyias-cov kinase inhibition thiab cov nyhuv pro-oxidant. Sassi N, Mattarei A, Espina V, Liotta L, Zoratti M, Paradisi C, Biasutto L. Pharmacol Res. 2017 Lub Kaum Hli; 124: 9-19. doi: 10.1016 / j.phrs.2017.07.016. Epub 2017 Jul 17. PMID: 28728925
  • Indole carboxylic acid esters ntawm melampomagnolide B yog lub zog anticancer tus neeg sawv cev tawm tsam ob lub cev nqaij hlav hematological thiab cov kabmob. Bommagani S, Ponder J, Penthala NR, Janganati V, Jordan CT, Borrelli MJ, Crooks PA. Eur J Med Chem. 2017 Lub Yim Hli 18; 136: 393-405. doi: 10.1016 / j.ejmech.2017.05.031. Epub 2017 Tsib Hlis 11. PMID: 28525840 Free PMC Tshooj
  • Qhov Zoo tshaj Nootropic Tshooj Qhia: Txhua Yam Koj Yuav Tsum Tau Paub [5 Xyoo Kev Ua Haujlwm]

 

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