cov khoom siv

CAD-031 hmoov (2071209-49-7)

CAD-031 hmoov (CAD031) yog qhov tshiab ntawm lub hlwb nkag mus, J147-derivative uas tau txhim kho cov kev ua haujlwm neurogenic dhau J147 hauv tib neeg neural txheej txheem ua ntej (NPCs); tseem txhawb nqa kev faib cov NPCs hauv thaj tsam subventricular ntawm cov laus APPswe / PS1E9 nas; cawm cawm cov cortical neurons los ntawm oxytosis, thiab txo qis oxidative kev nyuaj siab nrog EC50 ntawm 20 nM; kuj tseem tiv thaiv kev poob lub zog hauv lub zog uas ua rau neuron cell tuag nyob rau hauv ib qho qauv hauv vitro ischemia nrog EC50 ntawm 47 nM; phiaj fatty acid metabolism thiab mob tshwm sim, ua kom pom kev ua tau zoo ntawm kev txawj ntse thiab muaj sia nyob hauv nas qauv ntawm AD.

Chaw Tsim Tshuaj: Batch Production
pob: 1KG / hnab, 25KG / nruas
Wisepowder muaj peev xwm tsim tau thiab muab khoom ntau. Txhua qhov kev tsim khoom raws li cGMP thiab kev tswj hwm nruj, tag nrho cov ntaub ntawv xeem thiab cov qauv muaj.

CAD-031 hmoov (2071209-49-7) video

 

CAD-031 hmoov (2071209-49-7) Cov Ntaub Ntawv Sau Npe

lub npe CAD-031 hmoov
CAS 2071209-49-7
purity 98%
Tshuaj lub npe Acetic acid, 2,2,2-trifluoro-, (2E) -1- (2,4-dimethylphenyl) -2 - [[3- (trifluoromethoxy) phenyl] methylene] hydrazide
Synonyms CAD 31); CAD-031 (CAD031)
molecular Formula C18H14F6N2O2
molecular Nyhav 404.312
Melting Point Tsis Muaj Cov Ntaub Ntawv
InChI Qhov Tseem Ceeb Tsis Muaj Cov Ntaub Ntawv
daim ntawv Tsis Muaj Cov Ntaub Ntawv
tsos Tsis Muaj Cov Ntaub Ntawv
Ib Sim Neej Tsis Muaj Cov Ntaub Ntawv
solubility Tsis Muaj Cov Ntaub Ntawv
cia mob -20 ° C XYUMX Hlis; 12 ° C 4 Hlis
Daim ntawv thov Tsis Muaj Cov Ntaub Ntawv
Kuaj Cov Ntaub Ntawv Qhov

 

CAD-031 hmoov (2071209-49-7) Cov Khoom Piav Qhia

CAD-031 hmoov tau zoo nyob rau hauv cov ntsiab lus ntawm kev tiv thaiv qee yam xwm txheej lom nyob hauv cov laus-cuam tshuam nrog cov kab mob neurodegenerative. CAD-031 hmoov muaj lub zog tiv thaiv kab mob tiv thaiv kab mob nyob rau hauv rau qhov sib txawv ntawm cov xovtooj ntawm tes uas ua rau pom kev lom nyob hauv lub hlwb qub. Kev tshawb fawb tshuaj thiab tshuaj lom lom ua ntej pom tias CAD-031 yog lub hlwb nkag mus thiab yuav nyab xeeb. Thaum pub rau cov laus, cov tsos mob APPswe/PS1ΔE9 AD nas pib ntawm 10 lub hlis ntawm hnub nyoog rau 3 lub hlis ntxiv hauv kev kho tus qauv ntawm tus kab mob, muaj kev txo qis hauv kev nco thiab lub hlwb. o, nrog rau kev nce ntxiv hauv kev qhia ntawm cov protein sib xyaw. Cov ntaub ntawv me me ntawm cov txheej txheem zom zaub mov los ntawm lub hlwb thiab ntshav pom tias qhov cuam tshuam loj ntawm CAD-031 yog nyob ntawm cov roj metabolism hauv thiab o. Txoj hauv kev txheeb xyuas cov ntaub ntawv qhia noob tau qhia tias CAD-031 muaj qhov cuam tshuam loj rau kev tsim cov kab mob sib kis thiab AD cov txheej txheem kev zom zaub mov.

 

CAD-031 (2071209-49-7) Kev Thov

  1. CAD-031 yog cov neuroprotective dav
  2. CAD-031 muaj cov ntaub ntawv muaj npe zoo thiab tshuaj nyab xeeb
  3. CAD-031 thim rov qab qee yam ntawm taub kev ua si tsis ua hauj lwm hauv cov laus transgenic AD nas
  4. RNA-seq kev tshuaj xyuas qhia tias CAD-031 hloov pauv qhov mob, kev noj qab haus huv, thiab, metabolism
  5. PAB-031 txo qhov mob thiab nce cov cim rau neurogenesis thiab synapses
  6. AD-31 lub hom phiaj lipid metabolism

 

CAD-031 (2071209-49-7) Kev siv

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