CAD-031 hmoov (2071209-49-7)

CAD-031 hmoov (2071209-49-7) video

CAD-031 hmoov (2071209-49-7) Cov Ntaub Ntawv Sau Npe

CAD-031 hmoov (2071209-49-7) Cov Khoom Piav Qhia

CAD-031 hmoov tau zoo nyob rau hauv cov ntsiab lus ntawm kev tiv thaiv qee yam xwm txheej lom nyob hauv cov laus-cuam tshuam nrog cov kab mob neurodegenerative. CAD-031 hmoov muaj lub zog tiv thaiv kab mob tiv thaiv kab mob nyob rau hauv rau qhov sib txawv ntawm cov xovtooj ntawm tes uas ua rau pom kev lom nyob hauv lub hlwb qub. Kev tshawb fawb tshuaj thiab tshuaj lom lom ua ntej pom tias CAD-031 yog lub hlwb nkag mus thiab yuav nyab xeeb. Thaum pub rau cov laus, cov tsos mob APPswe/PS1ΔE9 AD nas pib ntawm 10 lub hlis ntawm hnub nyoog rau 3 lub hlis ntxiv hauv kev kho tus qauv ntawm tus kab mob, muaj kev txo qis hauv kev nco thiab lub hlwb. o, nrog rau kev nce ntxiv hauv kev qhia ntawm cov protein sib xyaw. Cov ntaub ntawv me me ntawm cov txheej txheem zom zaub mov los ntawm lub hlwb thiab ntshav pom tias qhov cuam tshuam loj ntawm CAD-031 yog nyob ntawm cov roj metabolism hauv thiab o. Txoj hauv kev txheeb xyuas cov ntaub ntawv qhia noob tau qhia tias CAD-031 muaj qhov cuam tshuam loj rau kev tsim cov kab mob sib kis thiab AD cov txheej txheem kev zom zaub mov.

CAD-031 (2071209-49-7) Kev Thov

1. CAD-031 yog cov neuroprotective dav
2. CAD-031 muaj cov ntaub ntawv muaj npe zoo thiab tshuaj nyab xeeb
3. CAD-031 thim rov qab qee yam ntawm taub kev ua si tsis ua hauj lwm hauv cov laus transgenic AD nas
4. RNA-seq kev tshuaj xyuas qhia tias CAD-031 hloov pauv qhov mob, kev noj qab haus huv, thiab, metabolism
5. PAB-031 txo qhov mob thiab nce cov cim rau neurogenesis thiab synapses
6. AD-31 lub hom phiaj lipid metabolism

CAD-031 (2071209-49-7) Kev siv

1. Daugherty D, li al. Alzheimers Res Ther. 2017 Jul 14; 9 (1): 50.
2. Chen Q, Uantej M, Dargusch R, Roberts A, Riek R, Eichmann C, li al. Cov tshuaj neurotrophic tshiab rau kev txhim kho kev txawj ntse thiab Alzheimer tus kab mob. PLOS Ib. 2011; 6 (12): e27865. doi: 10.1371 / journal.pone.0027865. [PMC tsab xov xwm pub dawb] [PubMed] [CrossRef] [Google Scholar
3. Ua ntej M, Dargusch R, Ehren JL, Chiruta C, Schubert D. Cov tshuaj neurotrophic J147 thim rov qab kev txawj ntse puas hauv cov laus Alzheimer tus kab mob nas. Alzheimer's Res Ther. 2013; 5 (3): 25. ua: 10.1186/alzrt179. [PMC pub dawb tsab xov xwm] [PubMed] [CrossRef] [Google Scholar]
4. Ua ntej M, Chiruta C, Currais A, Goldberg J, Dargusch R, Maher P, li al. Rov qab rau yav tom ntej nrog kev kuaj ntshav phenotypic. ACS Chem Neurosci. Xyoo 2014; 5 (7): 503– doi: 10.1021 / cn500051h. [PMC tsab xov xwm pub dawb] [PubMed] [CrossRef] [Google Scholar
5. Uantej M, Goldberg J, Chiruta C, Farrokhi C, Kopynets M, Roberts AJ, li al. Xaiv rau neurogenic muaj peev xwm ua lwm txoj hauv kev rau Alzheimer tus kab mob tshuaj pom pom. Alzheimers Dement. 2016; 12 (6): 678– doi: 10.1016 / j.jalz.2016.03.016. [PMC tsab xov xwm pub dawb] [PubMed] [CrossRef] [Google Scholar
6. Currais A, Goldberg J, Farrokhi C, Tseej M, Uantej M, Dargusch R, li al. Muaj ntau hom kev mus cuag kev to taub txoj kev sib raug ntawm cov laus thiab cov dementia. Laus. 2015; 7 (11): 937– doi: 10.18632 / kev laus.100838. [PMC tsab xov xwm pub dawb] [PubMed] [CrossRef] [Google Scholar

Cov Lus Trending