cov khoom siv

Pterostilbene hmoov (537-42-8)

Pterostilbene yog ib yam tshuaj stilbenoid muaj feem nrog resveratrol. Nws yog cov pab pawg ntawm phytoalexins, cov neeg sawv cev tsim tawm los ntawm cov nroj tsuag los tua kab mob.Based ntawm kev tshawb fawb tsiaj nws yog xav tias muaj kev tiv thaiv mob qog nqaij hlav, tiv thaiv hypercholesterolemia, anti-hypertriglyceridemia zog, nrog rau lub peev xwm los tawm tsam thiab thim rov qab kev txawj ntse. Cov. Nws ntseeg tau tias cov compound tseem muaj cov khoom coj los tiv thaiv ntshav qab zib, tab sis tam sim no tsawg heev tau kawm txog.

Chaw Tsim Tshuaj: Batch Production
pob: 1KG / hnab, 25KG / nruas
Wisepowder muaj peev xwm tsim tau thiab muab khoom ntau. Txhua qhov kev tsim khoom raws li cGMP thiab kev tswj hwm nruj, tag nrho cov ntaub ntawv xeem thiab cov qauv muaj.

1.Dab tsi yog Pterostilbene?

2.Pterostilbene hmoov yog dab tsi?

3.Pterostilbene mechanism ntawm kev txiav txim yog dab tsi?

4.Pterostilbeneuse yog dab tsi?

5.Qhov txiaj ntsig ntawm kev noj Pterostilbene yog dab tsi?

6.Dab tsi yog cov txiaj ntsig ntawm Pterostilbene rau daim tawv nqaij?

7.Pterostilbene puas zoo rau lub hlwb?

8.Yog Pterostilbene zoo rau kev poob phaus

9.Pterostilbenenefits rau cov plaub hau kev loj hlob

10.Pterostilbene ntau npaum

11.Pterostilbene phiv

12.Pterostilbene rau kev ntxhov siab

13.Pterostilbene rau fertility

14.Pterostilbene rau dev

15.Cov khoom noj twg muaj Pterostilbene?

16.Pterostilbenederiv yog dab tsi?

17.Pterostilbenenatural qhov chaw

18.Pterostilbene yog phytoestrogen

19.Yog Pterostilbene rog soluble

20.Yog Pterostilbene dej soluble?

21.Pterostilbene puas nce LDL?

22.Pterostilbenelowder ntshav siab?

23.Pterostilbene puas txaus ntshai

24.Kuv yuav tsum noj Pterostilbene ntau npaum li cas?

25.Pterostilbene nrog lossis tsis muaj zaub mov?

26.Koj puas yuav noj Pterostilbene?

27.Lub sijhawm zoo tshaj plaws ntawm hnub noj Pterostilbene yog dab tsi?

28.Dab tsi ntxiv muaj Pterostilbene?

29.Pterostilbene puas zoo dua Resveratrol?

30.Leej twg yuav tsum tsis txhob noj resveratrol

31.Yuav ua li cas resveratrol muaj kev nyab xeeb?

32.Pterostilbene nrog caffeine

33.Pterostilbene nrog quercetin

34.Pterostilbene vs berberine

35.Pterostilbene thiab NMN

36.Pterostilbene thiab Nicotinamide riboside

37.Qhov twg yuav Pterostilbene?

 

Pterostilbene hmoov (537-42-8) video

 

Pterostilbene hais tau zoo dua li resveratrol. Lawv hu nws zaj ntshav, lossis txawm tias tus ciav ntawm cov hluas. Koj puas xav paub ntau ntxiv txog Pterostilbene? Nov yog 37 FAQ koj yuav tsum paub:

 

1. Pterostilbene yog dab tsi?

Pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene) yog ib qho tshwm sim polyphenol, ib hom molecule uas tshwm sim hauv cov nroj tsuag. Nws yog ib feem ntawm stilbene pawg ntawm cov tebchaw thiab lub ntsiab antioxidant tivthaiv ntawm blueberries. Hauv cov nroj tsuag, nws ua haujlwm tiv thaiv kab mob antimicrobial thiab feem ntau ua haujlwm tiv thaiv oxidative.

Pterostilbene tau pom thawj zaug hauv xyoo 1977 los ntawm Langcake thiab Pryce thiab tau kawm txog nws cov khoom antioxidant thiab cov txiaj ntsig kev noj qab haus huv.

Pterostilbene yog tshuaj muaj feem xyuam rau resveratrol, lwm yam khoom noj khoom haus nrov; Qee qhov kev tshawb fawb qhia tias nws yuav muaj txiaj ntsig zoo rau kev noj qab haus huv dua li nws cov kev sib raug zoo, qee zaum ua rau muaj kev tawm tswv yim tias nws yuav yog "zoo dua resveratrol".

 

Cov txiaj ntsig tseem ceeb ntawm Pterostilbene tuaj yeem ua tiav raws li hauv qab no:

1 Pterostilbene yog ib yam khoom ntuj pom nyob rau hauv me me hauv zaub thiab txiv hmab txiv ntoo xws li blueberries.
2 Pterostilbene yog ib qho me me molecule uas zoo dua li resveratrol ntawm kev nqus thiab ruaj khov.
3 Pterostilbene ncua lifespan nyob rau hauv ntau yam kab mob.
4 Pterostilbene tuaj yeem txo qhov mob.
5 Pterostilbene tuaj yeem txhim kho DNA kho.
6 Pterostilbene tuaj yeem qhib sirtuins, uas yog cov enzymes uas kho DNA, txhim kho cov metabolism thiab tuaj yeem txuas ntxiv kev noj qab haus huv thiab kev ua neej.
7 Pterostilbene tuaj yeem txhim kho lub hlwb ua haujlwm thiab tuaj yeem tiv thaiv lub hlwb.
8 Pterostilbene tuaj yeem txo cov protein ntau ntxiv, uas yog ib qho ntawm cov tsav tsheb ntawm kev laus.
9 Pterostilbene activates AMPK, ib qho tseem ceeb enzyme uas tuaj yeem tiv thaiv cov hlwb tiv thaiv kev laus.
10 10. Pterostilbene tsub kom zus tau tej cov haib antioxidant enzymes, tiv thaiv lub hlwb tiv thaiv oxidative puas.

 

2. Pterostilbene hmoov yog dab tsi? 

Pterostilbene hmoov yog cov khoom siv raw ntawm Pterostilbene nrog xim dawb.

 

Pterostilbene hmoov (537-42-8) Cov ntaub ntawv hauv paus

lub npe Pterostilbene hmoov
CAS tooj 537-42-8
purity 98%
Tshuaj lub npe Pterostilbene (Dimethylresveratrol)
Synonyms 3,5-Dimethoxy-4-stilbenol, 3,5-Dimethoxy-4-hydroxy-E-stilbene
molecular Formula C16H16O3
molecular Nyhav 256.3 g / mol
Melting Point 89-92 ° C
InChI Qhov Tseem Ceeb VLEUZFDZJKSGMX-ONEGZZNKSA-N
daim ntawv Dawb hmoov
Ib Sim Neej solubility
cia mob tiv thaiv los ntawm lub teeb, 2-8 ° C
Daim ntawv thov Kev npaj ua ntej, kev tawm dag zog lub cev, tshuaj pleev ib ce
COA, HPLC Qhov
Pterostilbene

hmoov

Pterostilbene-cov khoom02

 

 

3. Pterostilbene mechanism ntawm kev txiav txim yog dab tsi?

Pterostilbene yog polyphenol, ib hom molecule uas tshwm sim hauv cov nroj tsuag, tshwj xeeb yog cov txiv ntoo me me thiab noob txiv. Blueberries yog qhov muaj txiaj ntsig tshwj xeeb ntawm pterostilbene; Txawm hais tias nws pom nyob hauv txiv hmab, pterostilbene (tsis zoo li nws cov viv ncaus resveratrol) tsis muaj txoj sia nyob ntawm cov cawv txiv ntoo.

Dab tsi yog polyphenol? "Phenol" yog hais txog qee yam qauv tshuaj (hauv qhov no, hydroxyl pawg txuas nrog lub nplhaib benzene); "Poly" tsuas txhais tau hais tias cov lwg me me muaj ntau dua ib qho ntawm cov qauv. Ib qho ntawm polyphenols 'cov haujlwm tseem ceeb yog pab tsob ntoo tua cov pathogens. Thaum noj los ntawm tib neeg, polyphenols tuaj yeem ua cov tshuaj tua kab mob kom muaj zog.

Cov kws tshawb fawb tau paub txog phenols txij li thaum xyoo 19 -1867 - Joseph Lister, cov neeg pib siv tshuaj tua kab mob, tau tshaj tawm txog ib qho phenol tshuaj tua kab mob hauv xyoo 1894 - txawm hais tias lo lus "polyphenol" tsis muaj nws thawj zaug sau tseg txog xyoo XNUMX.

Ib yam li tus so ntawm polyphenols, cov neeg tshawb nrhiav tsis nkag siab li cas pterostilbene ua haujlwm. Dr. Jose M. Estrela, tus xibfwb ntawm kev paub txog lub cev ntawm lub tsev kawm hauv University of Valencia (Spain) uas tau kawm txog pterostilbene hais tias "qhov zoo yog tias pterostilbene ua haujlwm, tab sis qhov tsis zoo yog qhov peb tsis tuaj yeem piav qhia meej txog nws cov txiaj ntsig kev noj qab haus huv nrog cov ntaub ntawv uas peb muaj. "

 

4. Dab tsi yog Pterostilbene siv rau?

Pterostilbene tuaj yeem pab tiv thaiv Alzheimer's kab mob thiab kev laus ntawm kev paub txog kev poob qis, raws li kev tshawb fawb tsiaj uas luam tawm hauv Neurobiology of Aging hauv 2012. Hauv kev ntsuam xyuas cov nas, txoj kev tshawb fawb cov kws sau ntawv txiav txim siab tias pterostilbene tuaj yeem pab khaws cov kev txawj ntse, ib feem los ntawm kev txo qis. mob.

 

5. Cov txiaj ntsig ntawm kev noj Pterostilbene yog dab tsi?

Cov txiaj ntsig ntau ntawm pterostilbene hauv kev kho thiab tiv thaiv tib neeg cov kab mob tau raug ntaus nqi rau nws cov tshuaj tua kab mob antioxidant, tiv thaiv kab mob, thiab cov tshuaj tiv thaiv kab mob ua rau muaj kev txhim kho ntawm cov cell qub thiab inhibition ntawm malignant hlwb.

Ntau cov kev tshawb fawb tau pom tias muaj cov tshuaj tiv thaiv antioxidant, tiv thaiv kab mob, thiab cov tshuaj tiv thaiv kab mob ntawm pterostilbene, uas tau ua rau kev txhim kho ntawm cov hlwb noj qab haus huv thiab inhibition ntawm malignant hlwb.

 

1) Pterostilbene cov txiaj ntsig hauv plawv plawv

Pterostilbene tau cuam tshuam rau kev mob plawv. nrog ib txoj kev tshawb fawb qhia tias nws muaj kev tiv thaiv tiv thaiv atherosclerosis thiab lwm yam qhia tias nws txhim kho cov yam ntxwv ntawm autophagy thiab pab tiv thaiv cov pro-atherosclerosis nyhuv ntawm oxidized low-density lipoprotein ntawm vascular endothelial hlwb. Nws kuj tau pom tias muaj txiaj ntsig zoo hauv kev kho mob ischemia-reperfusion raug mob.

 

2) Pterostilbene cov txiaj ntsig hauv Tus kab mob Alzheimer

Cov kev tshawb fawb kuj tau qhia txog lub peev xwm ntawm pterostilbene nyob rau hauv kev sib raug zoo rau cov kab mob neurodegenerative xws li Alzheimer's kab mob. Kev tshawb fawb ntawm cov nas nrog nrawm nrawm pom tias pterostilbene, txawm tias nyob rau hauv cov koob tshuaj tsawg, muaj txiaj ntsig zoo rau kev txhim kho kev txawj ntse.

 

3) Pterostilbene tuaj yeem txhim kho kev paub

Lwm txoj kev tshawb fawb qhia tias pterostilbene koom nrog hauv neural plasticity thiab nws txoj kev paub thiab lub cev muaj zog thiab cov nas uas muab pterostilbene ua tau zoo dua hauv kev ntsuam xyuas kev txawj ntse.

 

4) Pterostilbene yog ib qho muaj zog tiv thaiv kab mob

Pterostilbene yog ib qho muaj zog tiv thaiv kab mob thiab tuaj yeem tiv thaiv NF-Kb, cov protein complex uas tswj cov kev hloov pauv ntawm DNA, cytokine ntau lawm thiab cell ciaj sia. Ib txoj kev tshawb fawb tsis ntev los no tau pom tias pterostilbene tuaj yeem kho tus mob pancreatitis mob hnyav los ntawm kev txo cov ntshav qab zib TNF-a, IL-1b, thiab NF-kB thiab tias nws txo qis kev tsim cov pa oxygen reactive.

Pterostilbene kuj muaj qee cov ntaub ntawv qhia tias nws yuav muaj txiaj ntsig zoo rau kev kho mob caj dab, thiab muab nws cov khoom tiv thaiv kab mob, qhov no tsis yog qhov xav tsis thoob. Thaum kev tshawb fawb tsuas yog txwv rau hnub tim txog kev mob caj dab, kev tshawb fawb nas tau qhia qee qhov peev xwm los kho tus mob no.

 

5) Pterostilbene tuaj yeem pab poob phaus

Ib txoj kev tshawb fawb tsis ntev los no ua rau cov neeg mob hypercholesterolemia, tsis noj tshuaj tiv thaiv cov roj (cholesterol), pom tias thaum ntxiv nrog Pterostilbene, cov kev xeem no qhia pom qhov poob phaus tseem ceeb. Cov ntsiab lus no mus rau qhov muaj txiaj ntsig poob phaus ntawm cov tshuaj lom neeg.

Lwm txoj kev tshawb fawb tau ua ntawm cov qauv tsiaj ntxiv nrog Pterostilbene hmoov pom tias muaj kev nce ntxiv hauv Akkermansia muciniphila cov pej xeem hauv plab ntawm tus tsiaj qauv. Qhov tseem ceeb ntawm hom no yog tias nws txo qhov kev pheej hmoo ntawm kev rog rog, thiab txhim kho kev noj qab haus huv tag nrho ntawm plab.

 

6) Pterostilbene txhim kho lub plawv ua haujlwm

Cov tshuaj tiv thaiv kab mob antioxidant ntawm Pterostilbene tshwj xeeb tshaj yog muaj txiaj ntsig hauv plawv, vim tias lawv txo qis kev ntxhov siab ntawm lub cev. Cov kev tshawb fawb ntawm tsiaj qauv tau qhia tias txo qis tseem ceeb ntawm lub plawv tsis ua haujlwm, uas yog los ntawm kev ntxhov siab ntawm lub plawv los ntawm kev ua haujlwm tsis zoo ntawm lub ntsws.

 

7) Pterostilbene tiv thaiv cov yam ntxwv rau lub zeem muag

Tam sim no, muaj ntau qhov kev tshawb fawb tsom mus rau lub peev xwm ntawm cov polyphenol no hauv kev txo qis qhov tshwm sim ntawm kev dig muag hauv cov neeg mob ntshav qab zib. Qhov xav tau rau txoj kev tshawb fawb no tau tshwm sim los ntawm lwm txoj kev tshawb fawb uas tau ua pov thawj tias Pterostilbene txo qhov mob hauv lub qhov muag. Qhov kev tshawb pom no tau coj mus rau cov kws tshawb fawb thawb rau kev siv Pterostilbene hmoov rau kev kho qhov muag qhuav.

 

6. Cov txiaj ntsig ntawm Pterostilbene rau daim tawv nqaij yog dab tsi?

Pterostilbene cream uas muaj Pterostilbene hmoov tau zoo heev los txo cov cim ntawm kev laus thiab induces txawm tawv nqaij. Cov khoom siv tau zoo hauv kev txo cov wrinkles thiab cov kab zoo, txhim kho daim tawv nqaij elasticity thiab tsis pom kev cuam tshuam

 

7. Puas yog Pterostilbene zoo rau lub hlwb? 

Yog lawm, Pterostilbene zoo rau lub hlwb. Pterostilbene tuaj yeem txhim kho lub hlwb ua haujlwm thiab tuaj yeem tiv thaiv lub hlwb. Pterostilbene tuaj yeem txo cov protein ntau ntxiv, uas yog ib qho ntawm cov tsav tsheb ntawm kev laus. Pterostilbene activates AMPK, ib qho tseem ceeb enzyme uas tuaj yeem tiv thaiv cov hlwb tiv thaiv kev laus.

 

8. Puas yog Pterostilbene zoo rau kev poob phaus

Pterostilbene tau tsim cov txiaj ntsig zoo rau kev poob phaus hauv tsawg kawg ib txoj kev tshawb fawb, tab sis kev tshawb fawb loj thiab muaj zog dua yuav tsum tau ua kom paub meej tias nws cov txiaj ntsig.

Hauv kev tshawb fawb ntawm cov neeg muaj hnub nyoog nruab nrab uas muaj cov roj cholesterol siab, cov neeg uas tsis noj cov tshuaj cholesterol poob qis me me, tab sis tseem ceeb, qhov hnyav thaum ntxiv nrog pterostilbene. Qhov txiaj ntsig no yog qhov xav tsis thoob, vim qhov kev tshawb fawb no tsis tau tsim los ntsuas pterostilbene raws li kev pab poob phaus. Cov txiaj ntsig no tseem tsis tau tshawb xyuas hauv ib qho kev tshawb fawb cais.

Kev tshawb fawb ntawm tes thiab tsiaj kuj qhia tias pterostilbene tuaj yeem pab txhim kho cov tshuaj insulin. Pterostilbene thaiv kev hloov dua siab tshiab ntawm cov suab thaj rau hauv cov rog thiab tiv thaiv cov rog rog los ntawm kev sib npaug.

Pterostilbene kuj tseem tuaj yeem hloov pauv cov kab mob hauv plab, cov kab mob ntawm cov kab mob uas nyob hauv txoj hnyuv thiab pab zom zaub mov.

Cov nas noj pterostilbene muaj kev noj qab haus huv hauv plab, suav nrog kev nce ntxiv hauv Akkermansia muciniphila, ib hom kab mob uas tshwm sim los tiv thaiv kev rog rog, ntshav qab zib, thiab qis qis. A. muciniphila tsis ntev los no tau dhau los ua qhov tseem ceeb ntawm kev tshawb fawb probiotic; Cov kev tshawb fawb yav tom ntej yuav qhia meej seb pterostilbene txhawb nws txoj kev loj hlob li cas.

 

9. Pterostilbene txiaj ntsig rau cov plaub hau loj hlob

Kev noj qab haus huv, noj zaub mov zoo yog qhov tseem ceeb rau lub taub hau noj qab haus huv ntawm cov plaub hau. Sau cov khoom noj uas muaj protein ntau thiab cov vitamins yuav pab txhim kho koj cov tawv nqaij thiab txhim kho koj txoj kev noj qab haus huv tag nrho, thiab tau kawg, khaws lub qhov muag rau resveratrol lossis Pterostilbene. Yog tias nws yog plaub hau poob koj tab tom tsom rau tam sim no, koj yuav xav qhia cov tshuaj ntxiv rau hauv koj li niaj hnub. Ntxiv uas ua ke ntawm cov zaub mov thiab cov vitamins uas txhawb nqa tawv taub hau thiab pab txhawb cov plaub hau noj qab haus huv.

 

Nov yog qee yam ntxiv uas koj tuaj yeem ua los txhawb koj thiab koj cov plaub hau:

- Tawv massage

Kev zaws tawv taub hau zoo tuaj yeem pab tshem tawm qhov nro ntawm lub taub hau ntawm lub taub hau, thiab tsis yog nws zoo nkaus li zoo, kev tshawb fawb qhia tias yog tias koj ua tsis tu ncua, koj kuj yuav muaj cov plaub hau tuab. Zoo, yog tias koj tawm tsam nrog alopecia, tawv taub hau massage tsom rau cov plaub hau follicle, uas pom nyob rau hauv qab ntawm daim tawv nqaij. Thaum cov follicles no tau txhawb nqa, cov hlab ntsha yog dilated thiab cov plaub hau loj hlob (tej zaum) tshwm sim.

Massage koj cov tawv taub hau ob peb zaug hauv ib lub lis piam hauv da dej los pab txhawb koj cov plaub hau thiab pab koj so. Los yog siv nws los ua haujlwm hauv koj cov tshuaj pleev plaub hau uas koj nyiam los yog ua npuas ncauj los pab nthuav cov khoom thiab pab nrog kev nqus thiab cov ntshav.

 

- Txo kev ntxhov siab.

Lub ntiaj teb tuaj yeem yog qhov chaw nyuaj, thiab hmoov tsis zoo, yog tias koj pom koj tus kheej nyob rau hauv ib qho kev ntxhov siab loj, koj tuaj yeem pom cov plaub hau poob ntau dua li niaj zaus. (Zoo li tej yam tsis yooj yim txaus!) Cov kev ntxhov siab tuaj nyob rau hauv txhua daim duab thiab qhov ntau thiab tsawg - tej zaum koj tab tom cuam tshuam nrog kev ua haujlwm nyuaj, lossis tej zaum koj nyob nrog cov teeb meem nyiaj txiag. Txawm li cas los xij, yog tias koj tsis nrhiav sijhawm los so kom zoo, koj tuaj yeem ntsib kev mob tshwm sim ntawm lub cev.

Telogen effluvium yog hom plaub hau poob feem ntau cuam tshuam nrog kev ntxhov siab. Koj tseem tuaj yeem ntsib Alopecia areata (cov plaub hau poob hauv qee qhov chaw), Trichotillomania (cov plaub hau rub) thiab Androgenic alopecia (thinning plaub hau). Xyuas kom koj noj qab nyob zoo thiab ua haujlwm ntawm koj txoj kev pw tsaug zog kom txhawb lub xeev txaus thiab so tob.

 

10. Pterostilbene ntau npaum

Kev ntxiv ntawm pterostilbene rau lub hom phiaj ntawm kev pab cov piam thaj thiab lipid metabolism zoo li nyob ib ncig ntawm 20- 40mg / kg qhov ncauj noj hauv nas, uas yog kwv yees tib neeg ntau npaum li cas ntawm:

215-430mg rau 150lb tus neeg

290-580mg rau 200lb tus neeg

365-730mg rau 250lb tus neeg

 

Muaj peev xwm anxiolytic zog ntawm pterostilbene pom ntawm 1-2mg / kg hauv nas, uas yog kwv yees tib neeg koob tshuaj ntawm:

5.5-11mg rau 150lb tus neeg

7.3-14.5mg rau 200lb tus neeg

9-18mg rau 250lb tus neeg

Uas yog qhov tseem ceeb li 5-10mg / kg hauv cov nas no (me ntsis ntau dua ob koob tshuaj) tau ua tsis tau zoo tib yam kev ntxhov siab, tawm tswv yim lub tswb-kov uas yuav nyiam cov tshuaj qis dua xws li pom hauv kev noj zaub mov ntau dua li ntau dua los ntawm kev pab ntxiv.

Tib neeg txoj kev tshawb fawb tau siv 50mg ob zaug hauv ib hnub lossis 125mg ob zaug hauv ib hnub, thiab qhov sib ntxiv ntawm Grape noob extract (100mg ntawm ob lub sijhawm noj) nrog cov koob tshuaj tsawg yuav txo tau qee qhov tsis zoo ntawm cov roj (cholesterol) pom nrog pterostilbene hauv kev sib cais.

 

11. Pterostilbene phiv

Piv nrog rau cov tshuaj uas tau sau tseg los kho cov tsos mob xws li cov roj (cholesterol) siab thiab lwm yam teeb meem kev noj qab haus huv, pterostilbene yuav tsis tshua muaj tshwm sim (xws li mob nqaij thiab xeev siab). Nws feem ntau muaj kev nyab xeeb los ntawm cov khoom noj thiab tshuaj ntxiv, tab sis nyob rau hauv cov koob tshuaj ntau nws yuav cuam tshuam rau cov teebmeem ntawm qee yam tshuaj.

Yog tias koj noj tshuaj los pab tswj koj cov roj cholesterol, ntshav siab thiab / lossis cov ntshav qabzib, nws yog qhov zoo tshaj plaws los tham nrog koj tus kws kho mob ua ntej pib cov tshuaj tshiab. Koj tus kws kho mob tuaj yeem pab saib xyuas koj cov tshuaj tiv thaiv yog tias koj xaiv pib noj cov tshuaj pterostilbene kom paub tseeb tias koj qhov koob tshuaj tsis tas yuav hloov kho.

Txawm tias thaum noj tshuaj ntau, pterostilbene tau pom tias feem ntau tsis muaj tshuaj lom. Txawm li cas los xij, koob tshuaj siab tsis zoo li muab cov txiaj ntsig ntxiv, uas yog vim li cas koj yuav tsum ua raws li cov lus pom zoo noj, thiab raws li kev tshawb fawb luam tawm hauv Phau Ntawv Xov Xwm ntawm Toxicology, "qhov muaj peev xwm rau toxicity tsis tuaj yeem suav nrog ntau dua." Tsis txhob noj cov tshuaj pterostilbene yog tias koj muaj xeev siab, mob, khaus khaus lossis cov tsos mob txawv txawv. Yog tias koj muaj kev fab tshuaj rau cov khoom noj pterostilbene xws li txiv laum huab xeeb, txiv laum huab xeeb lossis txiv hmab txiv ntoo, koj yuav tsum tsis txhob noj cov zaub mov no txawm tias lawv raug suav hais tias "zoo."

 

12. Pterostilbene rau kev ntxhov siab

Pterostilbene yog ib qho extract los ntawm blueberries, yog li nws ua raws li lub zog tiv thaiv oxidant. Nws tswj los yog pab kom sib npaug cov paj hlwb thiab chemistry nyob rau hauv lub hippocampus, uas nyob rau hauv lem tswj kev nco. Pterostilbene pab muab kev xav thiab kev nco zoo li "tsis muaj kev ntxhov siab," ua rau koj xis nyob dua. Koj tuaj yeem noj cov tshuaj Pterostilbene txhua hnub.

 

13. Pterostilbene rau fertility

Ib tug poj niam lub qe yog tsim thaum nws tus kheej nyob rau hauv utero. Raws li cov qe loj hlob tuaj, lawv cov DNA ua tsis yooj yim dua thiab ua rau muaj kev puas tsuaj rau chromosomal. Qhov kev puas tsuaj chromosomal no yog qhov ua rau poob cev xeeb tub thoob plaws txhua pawg hnub nyoog, thiab kev pheej hmoo ntawm nchuav menyuam yuav nce ntxiv thaum ib tus laus dua. Hnub nyoog yog tus naj npawb ib yam cuam tshuam rau tus poj niam fertility.

Pterostilbene yog ib qho muaj zog antioxidant uas tau pom kev pab nrog qe zoo. Nws yooj yim heev rau noj thiab tsis muaj tus neeg mob qhia txog kev phiv tshuaj.

Resveratrol yog ib qho tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tiv thaiv kab mob, thiab insulin-sensitizing natural polyphenolic compound. Cov pov thawj loj hlob qhia tau hais tias resveratrol muaj peev xwm kho tau cov kev mob tshwm sim hauv cov poj niam cev xeeb tub nrog kev txo qis ntawm zes qe menyuam, polycystic zes qe menyuam syndrome (PCOS), lossis endometriosis.

Ib sab ntawm kev siv Pterostilbene lossis Resveratrol ntxiv, txoj kev ua neej zoo yog qhov zoo rau kev xeeb tub thiab. Piv txwv li:

-pw tsaug zog

Qhov peb kawm ntau ntxiv txog kev pw tsaug zog, qhov ntau peb pom tias yim lossis ntau teev txhua hmo yog xav tau rau kev noj qab haus huv zoo. Qhov no tshwj xeeb tshaj yog rau peb cov qe. Peb lub cev yog tsim los sawv nrog lub hnub thiab mus pw thaum tsaus ntuj. Kev pw tsaug zog txaus yog qhov tseem ceeb rau kev sib npaug ntawm cov tshuaj hormones, uas txhawb nqa kev loj hlob ntawm qe. Pw tsaug zog kuj tseem ua lub luag haujlwm tseem ceeb hauv kev tswj qhov hnyav, txhawb nqa lub zog zoo, thiab txo kev ntxhov siab.

 

-Ib ce muaj zog

Qee qhov kev tawm dag zog zoo, tab sis ntau dhau tuaj yeem tiv thaiv koj thaum koj xav xeeb tub. Lub cev muaj ob lub zog:

Sib ntaus-lossis-flight

Pub thiab yug

Kev tawm dag zog hnyav ua rau lub cev mus rau hauv hom kev sib ntaus sib tua. Qhov no cuam tshuam rau koj cov tshuaj hormones, inhibits qe kev loj hlob, thiab ua rau nws nyuaj rau cev xeeb tub. Kev tawm dag zog me me mus rau nruab nrab, xav txog kev taug kev lossis yoga maj mam, ua kom koj cov ntshav ncig thaum tswj koj lub cev nyob rau hauv hom pub-thiab-loj hlob.

 

14. Pterostilbene rau dev

Piv rau cov ntaub ntawv hais txog Pterostilbene rau dev, cov ntaub ntawv ntau ntxiv yog hais txog Resveratrol rau dev. Ib txoj kev tshawb fawb tau ua nyob rau xyoo 2015 pom tias resveratrol ob qho tib si boosts thiab suppresses lub cev tsis muaj zog. Resveratrol ua rau cov qe ntshav dawb tso tawm ntau cov cytokines pro-inflammatory dua li niaj zaus. Cov qe ntshav dawb siv cov cytokines sib txuas lus thaum sib ntaus sib tua. Qhov ntau cytokines muaj, lub zog tiv thaiv kab mob.

Txawm li cas los xij, resveratrol ib txhij inhibits lub cev tiv thaiv kab mob los ntawm kev txo qis kev ua haujlwm ntawm neutrophils. Cov qe ntshav dawb no sib ntaus thiab tua cov kab mob thaum muaj kab mob. Cov kev tshawb pom tsis sib haum no ua rau nws nyuaj dua los txiav txim siab seb resveratrol puas muaj txiaj ntsig zoo rau lub cev tiv thaiv kab mob.

Cov tshuaj kuj tseem tuaj yeem tiv thaiv qog noj ntshav, tshwj xeeb tshaj yog cov qog nqaij hlav hauv plab thiab lub mis, los ntawm kev tiv thaiv thiab ua kom qeeb ntawm cov qog nqaij hlav cancer. Resveratrol kuj tseem muaj cov tshuaj tiv thaiv kab mob siab, thiab tuaj yeem tiv thaiv ntshav siab thiab roj cholesterol. Nws kuj tau xav tias yuav txhawb nqa kev noj qab haus huv neurological, txawm tias qhov no tsis tau lees paub. Qee qhov kev tshawb fawb qhia tias nws tuaj yeem ua rau tus tsiaj muaj sia nyob.

Thaum cov kev tshawb pom no zoo li pheej hmoo, cov kws kho tsiaj tseem tab tom tshawb xyuas tag nrho cov teebmeem ntawm resveratrol ntawm lub cev tiv thaiv kab mob. Nws tsis paub meej tias kev tswj hwm ntev npaum li cas ntawm cov tshuaj resveratrol ua rau muaj kev phom sij rau dev thiab lwm yam tsiaj. Kev tshawb fawb ntxiv yog xav tau los txiav txim siab qhov tshwm sim ntawm qhov sib xyaw ua ke, tsis yog hauv cov dev xwb tab sis hauv txhua tus tsiaj.

Tsis tas li ntawd, yuav luag tag nrho cov kev tshawb fawb uas qhia tias resveratrol feem ntau muaj txiaj ntsig tau ua rau cov kab mob qog noj ntshav, txiv hmab txiv ntoo yoov, ntses, thiab nas. Txawm hais tias cov kev tshawb fawb pom tias resveratrol nce cov tsiaj no lub neej, resveratrol feem ntau yuav cuam tshuam rau dev sib txawv. Muaj qee qhov kev tshawb fawb txog qhov cuam tshuam ntawm resveratrol hauv dev.

Ntau cov kev tshawb fawb tseem pom zoo txog cov txiaj ntsig kev noj qab haus huv ntawm resveratrol rau ob leeg canines thiab tib neeg. Txawm li cas los xij, nws yuav tsis yog qhov txuj ci tseem ceeb ntxiv qee qhov chaw lees tias nws yog.

Feem ntau cov dev noj qab nyob zoo yuav tsis xav tau resveratrol supplementation, tshwj xeeb tshaj yog vim resveratrol yuav tsum tau noj tsawg heev. Yog tias koj xav ntxiv me ntsis ntxiv resveratrol rau koj tus dev noj, xav txog kev pub mis rau lawv blueberries los yog txiv laum huab xeeb. Ob qho khoom noj muaj cov resveratrol ib txwm muaj, ntxiv rau cov vitamins, minerals, thiab lub plawv zoo antioxidants.

Tsis txhob muab tshuaj ntxiv rau koj tus dev tshwj tsis yog qhia meej meej kom ua li ntawd los ntawm kws kho tsiaj. Yog tias koj ntseeg tias koj tus dev yuav tau txais txiaj ntsig los ntawm cov tshuaj resveratrol ntxiv, nug koj tus kws kho tsiaj txog cov txiaj ntsig thiab teeb meem ua ntej koj yuav khoom noj lossis hloov koj tus dev noj. Tsuas yog muab cov tshuaj ntxiv hauv cov koob tshuaj pom zoo los ntawm koj tus kws kho tsiaj.

 

15. Cov zaub mov twg muaj Pterostilbene? 

Pterostilbene muaj nyob rau hauv blueberries, nrog rau kwv yees cov ntsiab lus ntawm ib blueberry txawv ntawm 99 ng txog 520 ng, nyob ntawm seb hom blueberry. Txhawm rau muab qhov no rau hauv kev xav, qhov nruab nrab blueberry punnet hnyav ib ncig ntawm 340 grams.

Yog tias koj noj tag nrho cov punnet, tag nrho cov nyiaj pterostilbene koj yuav tau txais tsuas yog 0.03 txog 0.18 mg, thiab raws li cov koob tshuaj siv hauv tib neeg kev tshawb fawb ntawm 100mg ib hnub twg, qhov ntawd yuav yog ib qho loj ntawm blueberries ib hnub!

Txawm li cas los xij, yog tias koj tab tom nrhiav kom tau txais cov qib ntawm pterostilbene uas cov khoom noj muaj txiaj ntsig, ces koj yuav tsum nyiam blueberries, tsis txhob hais txog tus nqi siab ntawm kev yuav txiv hmab txiv ntoo ntau. Nyob rau hauv qhov tseeb, qhov no yog impractical. Kev noj tshuaj ntxiv yog los ntawm 50 mg mus rau 1,000 mg rau ib ntsiav tshuaj.

Pterostilbene kuj pom muaj nyob rau hauv almonds, txiv hmab txiv ntoo nplooj thiab vines, cranberries thiab lwm yam Vaccinium berries, xws li lingonberries, bilberries, thiab huckleberries.

 

16. Dab tsi yog Pterostilbene tau los ntawm?

Pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene) yog ib qho stilbene compound uas zoo ib yam li lwm cov stilbenes nrov xws li resveratrol lossis piceatannol; Nws yog lub npe hu ua tom qab nws thawj zaug pom qhov chaw (pterocarpus genus) tab sis kuj yog ib feem ntawm blueberries thiab txiv hmab txiv ntoo. Nws yog phytoalexin (cov tshuaj tsim los ntawm cov nroj tsuag los tiv thaiv kab mob thiab kab) zoo ib yam li resveratrol txawm tias muaj zog dua.

 

Pterostilbene qhov chaw muaj xws li:

Pterocarpus marsupium (Indian Kino Tsob Ntoo) thiab pterocarpus santalinus (Sandalwood)
Blueberries (92-550ng / g qhuav hnyav)
Grape (Vitis vinifera) nplooj thiab berries
Anogeissus acuminata
Lub genus Dracaena
Rheum rhaponticum (hauv paus)
Peanuts (Arachis hypogaea)

 

17. Pterostilbene tej yam ntuj tso los

Pterostilbene muaj nyob rau hauv almonds, ntau yam Vaccinium berries (xws li blueberries), txiv hmab txiv ntoo nplooj thiab vines, thiab Pterocarpus marsupium heartwood.

 

18. Yog Pterostilbene yog phytoestrogen

Tsev neeg stilbenes ntawm phytoestrogens suav nrog reseveratrol thiab pterostilbene uas feem ntau pom muaj nyob rau hauv liab cawu cub thiab txiv laum huab xeeb.

 

19. Yog Pterostilbene rog soluble 

Yog lawm, qhov no yog ib qho ntawm qhov sib txawv ntawm Pterostilbene thiab Resveratrol kuj.Yog tsis muaj methoxy pawg Resveratrol tsis yog lipophilic (roj-soluble) li pterostilbene, yog li nws cov cellular uptake yog ntau tsawg dua pterostilbene - pterostilbene tuaj yeem raug coj los ntawm cov cell lipid bi. - txheej yooj yim dua.

 

20. Puas yog Pterostilbene dej soluble?

Pterostilbene yog xyaum insoluble (hauv dej) thiab tsis muaj zog acidic compound (raws li nws pKa). Pterostilbene tuaj yeem pom muaj nyob hauv cov txiv hmab txiv ntoo thiab txiv hmab txiv ntoo, uas ua rau pterostilbene muaj peev xwm biomarker rau kev noj cov khoom noj no.

 

21. Puas yog Pterostilbene nce LDL? 

Yog lawm, Pterostilbene nce LDL thaum siv hauv monotherapy. Pterostilbene txo cov ntshav siab hauv cov neeg laus ntawm 250 mg / hnub koob tshuaj. Zoo li muaj peev xwm txo qhov hnyav hauv qee pawg sub nrog pterostilbene.

 

22. Puas Pterostilbene txo ntshav siab?

Ib daim ntawv ntawm pterostilbene, ib qho chaw pom muaj nyob hauv blueberries, txo cov ntshav siab hauv cov neeg laus, raws li cov txiaj ntsig ntawm kev sim tshuaj tau nthuav tawm Lub Cuaj Hli 20 ntawm American Heart Association's 2012 Kev Tshawb Fawb Txog Kev Tshawb Fawb Ntshav Siab hauv Washington, DC

Txoj kev tshawb fawb randomized, ob qhov muag tsis pom kev, kev tswj hwm cov placebo tau ua los ntawm University of Mississippi Lub Tsev Kawm Ntawv ntawm Pharmacy thiab Tsev Kawm Ntawv Cov Kws Tshawb Fawb los txiav txim siab seb pterostilbene (tero-STILL-bean), txhim kho cov hlab plawv.

Cov kws tshawb nrhiav tau soj ntsuam cov khoom xyaw hauv 80 tus neeg mob uas muaj cov roj (cholesterol) tag nrho ntawm 200 lossis ntau dua thiab / lossis LDL cholesterol ntawm 100 lossis ntau dua). Ob zaug ib hnub twg rau rau mus rau yim lub lis piam, cov neeg koom tau txais ntau (125 mg) koob tshuaj pterostilbene, qis (50 mg) koob tshuaj pterostilbene, pterostilbene (50 mg) nrog txiv hmab txiv ntoo extract (100 mg), los yog cov placebo, hais tias Daniel M. Riche, tus thawj coj ntawm kev tshawb nrhiav. Cov kws tshawb fawb tau soj ntsuam cov neeg mob ntshav siab, lub cev hnyav thiab cov ntshav lipids thaum pib thiab xaus ntawm lawv txoj kev koom tes hauv txoj kev tshawb no.

"Peb pom txo cov ntshav siab systolic thiab diastolic hauv cov neeg mob uas tau txais cov koob tshuaj pterostilbene siab thiab txo cov ntshav siab systolic hauv cov neeg mob uas tau txais cov tshuaj pterostilbene qis nrog cov txiv hmab txiv ntoo extract," said Riche, tus pab xibfwb ntawm kev coj noj coj ua thiab tshuaj ntawm lub tsev muag tshuaj. UM Medical Center hauv Jackson.

Cov neeg koom nrog cov koob tshuaj pterostilbene (250 mg ib hnub twg) tau ua tiav qhov txo qis hauv cov ntshav siab piv rau cov placebo: 7.8 mmHg hauv systolic BP (p tsawg dua 0.01) thiab 7.3 mmHg hauv diastolic BP (p tsawg dua 0.001).

 

23. Puas yog Pterostilbene txaus ntshai

Pterostilbene suav hais tias muaj kev nyab xeeb thiab tsis muaj kev phiv loj heev txog li 250 mg ib hnub twg. Qee tus neeg yuav tau nce LDL roj cholesterol thaum noj pterostilbene; grape noob extract negates cov nyhuv no thiab tej zaum yuav khub zoo nrog ib tug ntxiv pterostilbene.

Tam sim no tsis muaj kev tshawb fawb txog kev nyab xeeb ntawm pterostilbene rau cov menyuam yaus lossis rau cov poj niam cev xeeb tub lossis pub niam mis. Vim tias qhov sib xyaw no feem ntau pom hauv cov zaub mov thiab suav tias yog noj qab haus huv, me me ntawm pterostilbene yuav tsum muaj kev nyab xeeb rau leej twg; Txawm li cas los xij, kev ceev faj yog qhia thaum noj ntau dua.

Tham nrog koj tus kws kho mob ua ntej muab pterostilbene rau cov menyuam yaus lossis noj koj tus kheej yog tias koj cev xeeb tub lossis pub niam mis.

 

24. Kuv yuav tsum noj Pterostilbene ntau npaum li cas?

Pterostilbene feem ntau muaj kev nyab xeeb rau tib neeg siv ntawm koob tshuaj txog 250 mg ib hnub twg. Pterostilbene tau txais txiaj ntsig zoo ntawm ob zaug ib hnub koob tshuaj ntau zaus

 

25. Pterostilbene nrog lossis tsis muaj zaub mov?

Raws li txoj kev tshawb fawb uas yog thawj qhov tsim qauv zoo sib piv ntawm pterostilbene hauv kev tswj hwm tib neeg cov koob tshuaj. Zoo li tsis muaj kev cuam tshuam ncaj qha ntawm pterostilbene rau kev ntsuas ntawm lub siab lossis lub raum ua haujlwm.

Tsis zoo li muaj kev koom tes ntawm pterostilbene nrog plab hnyuv ADR (nrog lossis tsis muaj zaub mov) lossis khaus raws li ob qho tib si qhia ADRs tshwm sim rau qhov tsawg kawg nkaus hauv cov placebo thiab cov koob tshuaj siab.

 

26. Koj yuav tsum noj Pterostilbene?

Kev sim tib neeg tau pom tias pterostilbene muaj kev nyab xeeb txog li 250 mg ib hnub. Muab pov rau hauv qhov sib tov qhov tseeb tias nws feem ntau pom hauv cov zaub mov, thiab nws tau pom tseeb tias pterostilbene feem ntau muaj kev nyab xeeb siv. Nco ntsoov, txawm li cas los xij, tias cov tshuaj no nce qib 'phem' cholesterol hauv cov neeg siv.

 

27. Hnub twg yog lub sijhawm zoo tshaj plaws los noj Pterostilbene?

Cov neeg tuaj yeem nug "Thaum twg kuv tuaj yeem noj cov resveratrol, pterostilbene, curcumin thiab quercetin kom pom kev zoo? ”

Nws yog qhov zoo dua haus thaum sawv ntxov, lossis yav tsaus ntuj, tab sis tsis yog thaum nruab hnub. Noj nrog dej, nrog ib pluag mov me me (piv txwv li).

 

28. Cov tshuaj muaj dab tsi Pterostilbene?

Raws li tib neeg them nyiaj ntau dua thiab ntau dua rau kev noj qab haus huv, tib neeg qhov kev thov rau cov tshuaj ntxiv kuj nce ntxiv ib hnub. Cov tshuaj Pterostilbene yog ib qho ntawm lawv, uas yog hlub los ntawm tib neeg.

Cov khoom tseem ceeb ntawm Pterostilbene ntxiv ntawm chav kawm yog Pterostilbene hmoov, nws tuaj yeem siv los ua ntau yam, suav nrog tshuaj ntsiav, tshuaj, haus ...

Pterostilbene raws li methylated stilbene molecule, nws muaj cov qauv zoo sib xws rau cov antioxidant resveratrol. Pterostilbene thiab resveratrol sib koom ntau yam txiaj ntsig, suav nrog kev sib ntaus sib tua oxidative kev nyuaj siab, tab sis pterostilbene tau pom tias muaj bioavailability zoo dua. Hauv lwm lo lus, pterostilbene ntseeg tau tias yuav nqus thiab siv los ntawm lub cev yooj yim dua li cov phytonutrients zoo sib xws, uas yog ib qho laj thawj vim li cas nws tsis ntev los no tau txais kev saib xyuas ntawm cov kws tshawb fawb txog kev noj qab haus huv.

 

29. Puas yog Pterostilbene zoo dua Resveratrol?

1). Resveratrol yog dab tsi

Resveratrol yog ib feem ntawm ib pawg ntawm cov tshuaj hu ua polyphenols. Lawv tau xav tias yuav ua zoo li antioxidants, tiv thaiv lub cev tiv thaiv kev puas tsuaj uas tuaj yeem ua rau koj muaj kev pheej hmoo siab dua rau tej yam xws li mob qog noj ntshav thiab kab mob plawv. Resveratrol txhawb nqa kev noj qab haus huv ntawm cov hlab plawv, tiv thaiv antioxidant, qabzib metabolism, kev noj qab haus huv sib npaug, thiab lwm yam. Pterostilbene yog tam sim no championed raws li ib tug muaj zog daim ntawv nrog superior bioavailability.

 

Resveratrol hmoov (501-36-0) cov ntaub ntawv qhia

lub npe Resveratrol hmoov
CAS tooj 501-36-0
purity 98%
Tshuaj lub npe Resveratrol
Synonyms 5 - [(1E) -2- (4-Hydroxyphenyl) ethenyl] -1,3-benzenediol; trans-Resveratrol; (E) -5- (p-Hydroxystyryl) resorcinol; (E) -Resveratrol; trans-3,4 ′, 5-Trihydroxystilbene;
molecular Formula C14H12O3
molecular Nyhav 228.24 g / mol
Melting Point 243-253 ° C
InChI Qhov Tseem Ceeb LUKBXSAWLPMMSZ-OWOJBTEDSA-N
daim ntawv Dawb hmoov
Ib Sim Neej ntawm kev tshawb fawb, tawm tswv yim ib nrab neej txog li 1.6 teev
cia mob tiv thaiv los ntawm lub teeb, 2-8 ° C
Daim ntawv thov Cov cawv me me ntawm cov cawv, ze nrog kev txo cov ntshav lipid thiab kev txwv tsis pub platelet sib xyaw. Resveratrol yog qhov tshwj xeeb inhibitor ntawm COX-1, thiab nws tseem ua rau cov kev cuam tshuam hydroperoxidase ntawm COX-1. Nws tau pom tias inhibit cov xwm txheej cuam tshuam nrog cov qog pib, nce qib thiab nce zuj zus.
Pob duab
COA, HPLC Qhov

 

2). Pterostilbene vs Resveratrol

-Kev sib piv ntawm Bioavailability thiab Health Benefits

Ze li ob xyoos dhau los, nws tau pom tias resveratrol qeeb cov txheej txheem ntawm cellular aging nyob rau hauv poov xab. Hauv xyoo 2003, Harvard Medical School Professor David Sinclair, PhD, pom tias resveratrol ua rau lub neej ntev hu ua SIRT1 thiab cov txiaj ntsig ntawm cov proteins sirtuin.

Tom qab ntawd, tib lub tswv yim tau kawm thiab pom tias muaj tseeb hauv nas. Kev soj ntsuam rau hauv resveratrol ces tig mus rau nws cov teebmeem rau tib neeg noj qab haus huv. Resveratrol tau pom los txhawb kev mob plawv, tiv thaiv antioxidant, qabzib metabolism, noj qab haus huv sib npaug, thiab lwm yam. Raws li cov txiaj ntsig ntawm cov kev tshawb fawb no tau tshaj tawm, tib neeg tau nyiam haus dej cawv resveratrol-nplua nuj liab caw thiab noj cov tshuaj resveratrol.

Txawm li cas los xij, qee qhov teeb meem loj tshaj plaws rau kev sau cov txiaj ntsig ntawm resveratrol hauv tib neeg zoo li nws qhov kev txwv bioavailability thiab tshem tawm sai ntawm lub cev. Tab sis cov teeb meem no tej zaum yuav kov yeej los ntawm ib qho kev sib koom ua ke uas nyuam qhuav tau txais qee qhov kev ceeb toom.

Kwv yees li 10 xyoo tom qab kev tshawb pom tias resveratrol ua rau lub neej ntev, cov kws tshawb fawb tau pib nyiam nws cov kwv tij molecular, pterostilbene. Txawm hais tias nws yog tam sim no nyob rau hauv ib tug ntau dua concentration nyob rau hauv blueberries dua li nyob rau hauv liab cawu cub, pterostilbene yog ze li zoo tib yam nyob rau hauv cov qauv tshuaj rau resveratrol.

Thawj txoj kev tshawb fawb txog kev nyab xeeb ntawm tib neeg ntawm pterostilbene tau luam tawm xyoo 2013, thiab kev tshawb nrhiav tau nce ntxiv txij thaum ntawd los. Pterostilbene yog tam sim no championed raws li ib tug ntau haib daim ntawv ntawm resveratrol. Nws tau hais kom muab tag nrho cov txiaj ntsig yav dhau los paub ntawm resveratrol tab sis nrog bioavailability zoo dua. Cov lus thov no puas muaj tseeb? Nyeem rau kom paub meej qhov sib piv ntawm ob cov kwv tij txheeb ze.

 

-Cov qauv sib txawv 

Resveratrol thiab pterostilbene yog ob qho tib si ib txwm tshwm sim ntawm cov nroj tsuag. Resveratrol yog concentrated nyob rau hauv txiv hmab txiv ntoo tawv thiab liab cawu cub, tab sis nws kuj tau raug cais los ntawm cov hauv paus hniav ntawm Japanese knotweed. Pterostilbene yog concentrated feem ntau hauv blueberries, tab sis nws kuj tau pom muaj me me hauv txiv laum huab xeeb, txiv hmab txiv ntoo thiab cocoa.

Resveratrol thiab pterostilbene poob rau hauv chav kawm ntawm cov tshuaj hu ua stilbenes. Cov phenolic tebchaw no muaj ob lub nplhaib uas muaj ntxhiab nrog hydroxyl pawg (-OH). Resveratrol thiab pterostilbene zoo sib xws hauv cov qauv, tab sis nrog ib feeb - tseem ceeb heev - txawv. Resveratrol muaj peb pawg hydroxyl, thaum pterostilbene tsuas muaj ib. Lwm ob pawg hydroxyl yog hloov los ntawm methoxy pawg (O-CH3) hauv pterostilbene.

Qhov sib txawv ntawm cov pawg hydroxyl yog qhov tseem ceeb vim tias nws cuam tshuam sai npaum li cas cov tshuaj metabolized thiab tshem tawm ntawm lub cev. Peb pawg hydroxyl hauv resveratrol maj nrawm tshem tawm cov molecule, uas ua rau nws nyuaj kom ncav cuag thiab tswj kom muaj txiaj ntsig zoo ntawm resveratrol hauv cov hlab ntsha.

Nrog tsuas yog ib pawg hydroxyl ib molecule, pterostilbene muaj peev xwm nyob twj ywm rau hauv kev mus ntev. Qhov sib txawv me ntsis hauv cov qauv kuj ua rau pterostilbene ntau lipophilic. Pterostilbene tuaj yeem nkag tau yooj yim dua los ntawm cov cell membranes-ua kom muaj ntau dua los txhawb txoj hauv kev ntawm tes.

Ob leeg resveratrol thiab pterostilbene ib txwm tshwm sim hauv ob hom: cis thiab trans. Cov ntaub ntawv trans ruaj khov thiab muaj ntau dua hauv cov xwm txheej. Cov kev tshawb fawb qhia tias rau ob qho tib si resveratrol thiab pterostilbene, cov ntawv trans yog superior rau cis cov ntaub ntawv nyob rau hauv cov nqe lus ntawm lom lom.

 

-Bioavailability thiab Ib nrab-lub neej 

Cov xov xwm zoo txog resveratrol thiab pterostilbene yog tias lawv ob leeg tau yooj yim nqus tau tom qab noj qhov ncauj, thiab tseem muaj peev xwm hla cov ntshav-hlwb teeb meem. Cov xov xwm phem yog tias lawv tau metabolized sai heev. Lawv lub sijhawm nyob rau hauv kev ncig yog sai sai.

Qhov nqus ntawm resveratrol los ntawm txoj hnyuv lumen yog kwv yees li 75 feem pua, tab sis nws cov metabolism sai hauv daim siab ua rau lub qhov ncauj bioavailability ntawm tsuas yog 1 feem pua. Qhov ntawd yog vim lub siab tsim cov resveratrol conjugates - feem ntau glucuronides thiab sulfates. Hauv kev tshawb nrhiav tib neeg bioavailability, 15 tus neeg tuaj yeem noj qab haus huv txhua tus tau noj 500 mg capsule ntawm trans-resveratrol. Cov ntshav coj mus kuaj tom qab txhaj tshuaj tau pom tias cov resveratrol dawb tsuas yog sawv cev 0.28 feem pua ​​​​ntawm tag nrho cov resveratrol nyob rau hauv kev, nrog rau tus so muaj conjugated glucuronides los yog sulfates.

Txoj kev tshawb no tseem qhia tau hais tias resveratrol tau luv luv - nws cov concentration siab tshaj li ib teev tom qab noj. Cov txiaj ntsig ntawd zoo ib yam li kev tshawb fawb ua ntej, uas pom tias ib nrab-lub neej ntawm trans-resveratrol yog ib mus rau peb teev tom qab ib koob tshuaj.

Thaum ib tug compound muaj xws li tsis tshua muaj bioavailability thiab xws li ib tug luv luv ib nrab-lub neej, nws yog ib qho nyuaj rau tuav ib tug concentration nyob rau hauv kev. Ib txoj kev tshawb nrhiav pom tias txawm tias tib neeg noj 150 mg ntawm trans-resveratrol rau ib hnub, lawv tseem muaj cov ntshav plasma tsawg.

Ib qho ntawm feem ntau hais txog kev sib piv ntawm resveratrol thiab pterostilbene yog tias qhov ncauj bioavailability ntawm resveratrol tsuas yog 20 feem pua, thaum pterostilbene mus txog 80 feem pua. Tab sis nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias cov feem pua ​​​​ntawm cov feem pua ​​​​ntawm tag nrho cov resveratrol ntxiv rau resveratrol sulfate, thiab pterostilbene ntxiv rau pterostilbene sulfate. Nws tseem ceeb heev uas yuav tsum nco ntsoov tias cov feem pua ​​​​ntawm cov kev tshawb fawb no tau ua nyob rau hauv nas es tsis yog tib neeg.

Lwm qhov kev sib piv feem ntau yog tias ib nrab-lub neej ntawm pterostilbene yog xya npaug ntev dua li ntawm resveratrol. Qhov kev txheeb xyuas no los ntawm ob txoj kev tshawb fawb: Ib qho qhia tias resveratrol muaj ib nrab-lub neej ntawm 14 feeb, thiab lwm yam qhia tias pterostilbene muaj ib nrab-lub neej ntawm 105 feeb. Ntxiv dua thiab, cov no yog cov kev tshawb fawb preclinical uas tau ua tsis yog nyob rau hauv tib neeg tab sis nyob rau hauv luav, nas, thiab nas.

Ntau cov lus nug tseem tsis tau teb. Peb tsis paub tias cov metabolites conjugated ntawm resveratrol thiab pterostilbene muaj kev ua haujlwm lom neeg ntawm cov ntaub so ntswg (muaj qee cov pov thawj ntawm kev ua si, txawm tias tsawg dua li dawb resveratrol). Tsis tas li, nws tsis paub tias cov ntaub ntawv bioavailability ntawm pterostilbene los ntawm kev tshawb fawb tsiaj tuaj yeem muab txhais rau tib neeg.

Ntau tus kws tshawb fawb thiab kws kho mob tau noj cov ntaub ntawv txwv peb muaj txog tam sim no txog bioavailability ntawm pterostilbene thiab khiav nrog nws. Raws li cov kev tshawb fawb tau hais los saum toj no, pterostilbene tau txais lub koob npe nrov rau kev ua kom muaj zog dua thiab bioavailable daim ntawv ntawm resveratrol.

 

-Kev sib piv ntawm Kev Pabcuam Kev Noj Qab Haus Huv 

Resveratrol tau tshawb fawb ntau heev. Cov kev tshawb fawb tshawb fawb pom tau tias resveratrol hloov pauv ntau cov txheej txheem molecular ntawm qib cellular. Nws cuam tshuam, piv txwv li, nrog txoj hauv kev ntawm tes uas cuam tshuam nrog kev noj qab haus huv inflammatory tshuav, apoptosis, thiab autophagy. Nws kuj cuam tshuam nrog txoj hauv kev cuam tshuam nrog kev laus thiab kev ua neej ntev, xws li telomeres thiab cell senescence.

Txawm hais tias nws tsis tshua muaj bioavailability, muaj ntau cov pov thawj rau resveratrol lub peev xwm los txhawb kev noj qab haus huv ntawm tib neeg. Randomized, tswj kev sim tau pom tias resveratrol supplementation txhawb kev noj qab haus huv yuag, cov ntshav-qabzib metabolism, plawv ua haujlwm, mus ob peb vas, noj qab haus huv inflammatory tshuav nyiaj li cas thiab oxidative kev nyuaj siab. Resveratrol cov txiaj ntsig kev noj qab haus huv kuj tau pom nyob rau hauv ntau lwm yam kev tshawb fawb, thiab txawm tias meta-analyses.

Thaum nws los txog rau pterostilbene, cov pov thawj muaj ntau sparser. Ib cag los ntawm kev tshawb fawb txog kev nyab xeeb luam tawm xyoo 2013, muaj kev sim tsawg heev hauv tib neeg. Muaj ib txoj kev tshawb fawb, ua nyob rau hauv University of Mississippi hauv 80 tus neeg laus, uas pom tias pterostilbene txhawb kev noj qab haus huv ntshav siab thiab lipid metabolism.

Feem ntau ntawm kev tshawb fawb ntawm pterostilbene yog nyob rau hauv kev sim thiab preclinical theem. Cov kws tshawb fawb tau pom tias pterostilbene txhawb nqa ntau txoj hauv kev ntawm tes xws li resveratrol - suav nrog kev txhawb nqa kev tiv thaiv antioxidant thiab kev hloov pauv txoj hauv kev koom nrog kev noj qab haus huv inflammatory tshuav, apoptosis, thiab autophagy. Cov kws tshaj lij feem ntau pom zoo tias cov txheej txheem molecular ntawm pterostilbene yuav tsum suav tias yog sib npaug ntawm cov resveratrol.

 

30. Leej twg yuav tsum tsis txhob noj resveratrol

Cov neeg mob uas muaj ntshav tsis txaus, uas tuaj yeem ua rau los ntshav, yuav tsum tau saib xyuas los ntawm tus kws kho mob thaum noj cov khoom no. Cov neeg uas tab tom phais yuav tsum tsis txhob noj cov tshuaj resveratrol ob lub lis piam ua ntej kev phais thiab tsis txhob noj nws li ob lub lis piam tom qab kev phais kom txo tau cov ntshav los ntshav.

Tsis txhob noj cov tshuaj resveratrol lossis ntau cov khoom noj ntuj uas muaj resveratrol thaum cev xeeb tub lossis pub niam mis. Tsis muaj kev tshawb fawb hauv cheeb tsam no los ua pov thawj kev nyab xeeb. Resveratrol yuav tsum zam rau cov menyuam yaus.

Resveratrol muaj cov tshuaj estrogenic me me thiab kom txog thaum paub ntau ntxiv, cov poj niam uas mob qog noj ntshav thiab lwm yam mob uas estrogen rhiab heev yuav tsum nrhiav kev kho mob ua ntej noj resveratrol.

Resveratrol txo cov haujlwm ntawm cov enzymes koom nrog cov tshuaj metabolism tab sis seb nws puas muaj txiaj ntsig zoo rau tib neeg tsis tau kawm.

 

31. Muaj pes tsawg resveratrol muaj kev nyab xeeb?

Cov tshuaj Resveratrol tuaj yeem muaj kev nyab xeeb thaum noj los ntawm qhov ncauj hauv koob tshuaj txog 1500 mg ib hnub rau txog 3 lub hlis. Cov koob tshuaj ntau dua ntawm 2000-3000 mg txhua hnub tau siv yam xyuam xim rau 2-6 lub hlis. Tab sis cov koob tshuaj ntau dua no yuav ua rau mob plab.

 

32. Pterostilbene nrog caffeine

Caffeine yog methylxanthine pom nyob rau hauv taum kas fes, cocoa taum thiab hauv tshuaj yej. Kev tshawb fawb qhia tau tias caffeine yog lub hlwb stimulant uas ua rau muaj kev ceeb toom, wakefulness, mloog, ua hauj lwm nco, thiab lub cev muaj zog ua si.

Muaj cov khoom uas yog patented compound binding caffeine nrog lub zog antioxidant pterostilbene. Kev khi caffeine nrog pterostilbene ua rau qeeb qhov nqus ntawm caffeine ua kom ntev nws ib nrab lub neej thiab xa mus txog 30% ntau dua cov nyhuv thaum txo cov tsos mob caffeine tsoo.

 

33. Pterostilbene nrog quercetin 

1) quercetin yog dab tsi thiab nws cov txiaj ntsig

Quercetin yog cov nroj tsuag xim (flavonoid). Nws pom muaj ntau yam nroj tsuag thiab zaub mov, xws li cawv liab, dos, tshuaj yej ntsuab, txiv apples, thiab berries.

Quercetin muaj cov tshuaj tua kab mob antioxidant thiab tiv thaiv kab mob uas tuaj yeem pab txo qhov o, tua cov qog nqaij hlav cancer, tswj ntshav qab zib, thiab pab tiv thaiv kab mob plawv.

Quercetin feem ntau yog siv rau cov mob ntawm lub plawv thiab cov hlab ntsha thiab tiv thaiv kev mob qog noj ntshav. Nws kuj tseem siv rau kev mob caj dab, mob zais zis, thiab ntshav qab zib, tab sis tsis muaj pov thawj kev tshawb fawb muaj zog los txhawb feem ntau ntawm cov kev siv no. Kuj tsis muaj pov thawj zoo los txhawb kev siv quercetin rau COVID-19.

 

2) Pterostilbene vs Quercetin

Muaj cov chav tshwj xeeb ntawm cov tshuaj tiv thaiv antioxidant hu ua flavonoids lossis polyphenols, yog li kev noj zaub mov uas muaj txiv hmab txiv ntoo thiab tshwj xeeb tshaj yog zaub tuaj yeem mus ntev rau kev noj qab haus huv.

Quercetin thiab pterostilbene yog ob hom flavonoids. Txawm li cas los xij, vim tias cov tshuaj antioxidants no pom muaj tsawg heev hauv cov zaub mov nkaus xwb thiab koj lub cev muaj peev xwm nqus tau lawv hauv lawv lub xeev ntuj yog qhov tsis zoo lossis tsis txaus, koj lub peev xwm rau cov txiaj ntsig raug txwv.

Nrog Quercetin thiab Pterostilbene cov qauv siab heev, siv cov kev qhia txuj ci los ua kom cov compunds ' bioavailability ntau npaum li 20 npaug. Nrog cov mis tshwj xeeb, koj tuaj yeem tau txais:

1) Txhawb koj lub ntuj tiv thaiv tiv thaiv kev hem thawj raws caij nyoog.

2) Txhawb nqa kev noj qab haus huv ntawm lub ntsws thiab bronchial.

3) Txhawb kev tsim cov mitochondria tshiab hauv koj lub hlwb thiab cov leeg.

4) Txhawb kev noj qab haus huv, tiv thaiv kab mob.

5) Pab tiv thaiv cov hlwb thiab cov ntaub so ntswg tiv thaiv dawb radical puas.

6) Txhawb ib txwm inflammatory teb.

7) Txhim kho kev puas siab puas ntsws tom qab kev ntxhov siab ntawm lub cev.

8) Txhawb kev noj qab haus huv cellular aging.

9) Pab tiv thaiv lipid peroxidation hauv koj cov hlwb thiab cov ntaub so ntswg.

10) Txhawb kev noj qab haus huv metabolic.

 

34. Pterostilbene vs berberine 

Berberine yog ib qho bioactive compound uas tuaj yeem muab rho tawm los ntawm ntau cov nroj tsuag sib txawv, suav nrog cov nroj tsuag hu ua Berberis. HCL yog daim ntawv hydrochloride ntawm Berberine, CAS tus lej yog 633-65-8.

Txheej txheem, nws zwm rau ib chav kawm ntawm cov sib txuas hu ua alkaloids. Nws muaj cov xim daj, thiab feem ntau tau siv los ua zas xim.

Berberine muaj keeb kwm ntev ntawm kev siv tshuaj suav tshuaj, qhov twg nws tau siv los kho ntau yam mob.

Tam sim no, kev tshawb fawb niaj hnub no tau lees tias nws muaj txiaj ntsig zoo rau ntau yam teebmeem kev noj qab haus huv.

Pterostilbene yog ib yam khoom uas pom muaj tsawg heev hauv blueberries. Hauv qhov ntau, nws tuaj yeem txhim kho cov tshuaj insulin (R, R, R), thiab tuaj yeem txhim kho hom 2 mob ntshav qab zib (R, R).

Ib yam li metformin, pterostilbene tuaj yeem qhib AMPK (R). Qhov tseeb, pterostilbene activated AMPK twb nyob rau theem ntawm 50 micromolar, thaum metformin ua tiav cov nyhuv ntawm ntau dua koob tshuaj ntawm 2 millimolar (R).

 

35. Pterostilbene thiab NMN 

1) NMN yog dab tsi 

NMN stands rau nicotinamide mononucleotide, ib tug molecule ib txwm tshwm sim nyob rau hauv tag nrho cov hom ntawm lub neej. Nyob rau theem molecular, nws yog ribo-nucleotide, uas yog ib qho tseem ceeb ntawm cov qauv ntawm nucleic acid RNA. Raws li txoj cai, cov molecule yog tsim los ntawm ib pawg nicotinamide, ribose thiab phosphate pawg. NMN yog tus thawj coj ncaj qha ntawm qhov tseem ceeb molecule nicotinamide adenine dinucleotide (NAD +) thiab suav tias yog ib qho tseem ceeb hauv kev nce qib NAD + hauv hlwb.

NMN hmoov (1094-61-7) cov ntaub ntawv hauv qab

lub npe NMN hmoov
CAS tooj 1094-61-7
purity 99%
Tshuaj lub npe beta-Nicotinamide mononucleotide
Synonyms 3-Carbamoyl-1- [5-O- (hydroxyphosphinato) -β-D-ribofuranosyl] pyridinium
molecular Formula C11H15N2O8P
molecular Nyhav 334.221 g / mol
Melting Point > 96 ° C
InChI Qhov Tseem Ceeb DAYLJWODMCOQEW-TURQNECASA-N
daim ntawv Dawb hmoov
Ib Sim Neej /
cia mob Hygroscopic, -20˚C Lub Freezer, Nyob Hauv Kev Tshwm Sim
Daim ntawv thov Nicotinamide mononucleotide ("NMN", "NAMN", thiab "β-NMN") yog nucleotide muab los ntawm ribose thiab nicotinamide.
COA, HPLC Qhov
NMN hmoov Pterostilbene-cov khoom01

 

2) Pterostilbene nrog NMN 

Kev sib xyaw pterostilbene thiab NMN (nicotinamide mononucleotide) tuaj yeem yog lub zog duo rau kev ua kom cov txheej txheem kev laus qeeb. NMN yog qhov ua ntej rau NAD +, ib qho tseem ceeb coenzyme xav tau los ntawm txhua lub cell hauv lub cev. Kev txo qis hauv NAD + qib ua rau muaj kev nce qib ntawm kev laus thiab kab mob.

Ob leeg pterostilbene thiab NMN yog cov activators ntawm sirtuins, ib tsev neeg ntawm cov proteins uas tswj cov cellular thiab mitochondrial noj qab haus huv thiab tswj cov txheej txheem kev laus. Kev ua sirtuin nce ntxiv, tshwj xeeb tshaj yog SIRT1, tau txuas ntxiv rau kev ua neej nyob hauv cov poov xab thiab tsiaj txhu. Vim nws cov bioavailability zoo dua, pterostilbene tej zaum yuav muaj zog sirtuin activator dua resveratrol.

Kev sib xyaw ua ke pterostilbene thiab NMN tuaj yeem ua rau NMN qhov ua tau zoo vim tias sirtuin activators thiab NAD + boosters ua haujlwm ua ke. Raws li pterostilbene nce sirtuin kev ua si, ntxiv NMN tso cai rau lub precursor molecule ua nws thawj txoj hauj lwm ntawm boost NAD + ntau ntau.

Qhov tseem ceeb, NMN thiab pterostilbene ua haujlwm sib koom ua ke los txhim kho mitochondrial kev noj qab haus huv thiab ua rau cov txheej txheem kev laus qeeb, vim NMN txhawb nqa NAD + qib thiab ob qho tib si sib txuas ua sirtuins.

 

36. Pterostilbene thiab Nicotinamide riboside

1) Dab tsi yog Nicotinamide riboside(NR)

Nicotinamide riboside yog ib tug tswv cuab ntawm tsev neeg vitamin B3, uas kuj muaj xws li niacin thiab niacinamide. Nws muaj nyob rau hauv txiv hmab txiv ntoo, zaub, nqaij, thiab mis nyuj.

Nicotinamide riboside hloov pauv hauv lub cev mus rau cov tshuaj hu ua NAD +. Lub cev xav tau NAD + rau ntau cov txheej txheem ua haujlwm ib txwm. Qib qis tuaj yeem ua rau muaj teeb meem kev noj qab haus huv. Noj nicotinamide riboside tuaj yeem pab nce qib NAD + tsawg.

Tib neeg siv nicotinamide riboside los tiv thaiv kev laus, cov roj cholesterol siab, ntshav siab, Alzheimer kab mob, rog rog, thiab ntau lwm lub hom phiaj, tab sis tsis muaj pov thawj zoo los txhawb kev siv cov no.

Tsis txhob cuam tshuam nicotinamide riboside nrog niacin, niacinamide, lossis NADH. Cov no muaj feem cuam tshuam tab sis tsis zoo ib yam.

 

2) Pterostilbene nrog Nicotinamide riboside(NR)

Qee cov khoom noj muaj Pterostilbene thiab Nicotinamide Riboside (NR). Nicotinamide riboside yog ib qho ua ntej rau nicotinamide adenine dinucleotide (NAD +). Yog tias koj tab tom noj Pterostilbene nrog Nicotinamide Riboside "NR" (Kev Ntsuam Xyuas), koj yuav xav rov xav dua. NR tus kws tshaj lij Dr. Charles Brenner tau piav qhia hauv Twitter ua ntej.

 

37. Yuav qhov twg Pterostilbene?

Wisepowder ua cov chaw tsim khoom ncaj qha, muab qhov zoo tshaj plaws Pterostilbene hmoov los ntawm gram-KG-Ton los txhawb cov neeg siv khoom sib txawv.