cov khoom siv

Resveratrol hmoov (501-36-0)

Resveratrol (3,5,4′-trihydroxy-trans-stilbene) yog cov xyoob ntoo nyob hauv cov tawv nqaij liab, Japanese knotweed (polygonum cuspidatum), txiv laum huab xeeb, blueberries thiab qee yam txiv ntoo. Nws yog cov tshuaj muaj zog antioxidant tsim los ntawm qee cov nroj tsuag los tiv thaiv lawv tiv thaiv ib puag ncig kev ntxhov siab. Antioxidants neutralize dawb radicals, uas ntseeg tias yog vim li cas qhov pib ntawm kev laus. Japanese knotweed yog cov nroj tsuag nrog cov ntsiab lus resveratrol siab tshaj plaws.

Chaw Tsim Tshuaj: Batch Production
pob: 1KG / hnab, 25KG / nruas
Wisepowder muaj peev xwm tsim tau thiab muab khoom ntau. Txhua qhov kev tsim khoom raws li cGMP thiab kev tswj hwm nruj, tag nrho cov ntaub ntawv xeem thiab cov qauv muaj.
Qeb:

Resveratrol hmoov (501-36-0) video

 

 

Resveratrol hmoov Cov Ntaub Ntawv Los Ua Ntej

lub npe Resveratrol hmoov
CAS 501-36-0
purity 10% -98%
Tshuaj lub npe Resveratrol
Synonyms 5 - [(1E) -2- (4-Hydroxyphenyl) ethenyl] -1,3-benzenediol; trans-Resveratrol; (E) -5- (p-Hydroxystyryl) resorcinol; (E) -Resveratrol; trans-3,4 ′, 5-Trihydroxystilbene;
molecular Formula C14H12O3
molecular Nyhav 228.24
Melting Point 243-253 ° C (dec.)
InChI Qhov Tseem Ceeb LUKBXSAWLPMMSZ-OWOJBTEDSA-N
daim ntawv Khoom
tsos hmoov dawb nrog cov pov cam daj me me
Ib Sim Neej ntawm kev tshawb fawb, tawm tswv yim ib nrab neej txog li 1.6 teev
solubility Soluble hauv dej (3 mg / 100mL), ethanol (50 mg / mL), DMSO (≥16 mg / mL), DMF (~ 65 mg / mL), PBS (pH 7.2) (~ 100µg / mL), methanol, thiab acetone (50 mg / mL).
cia mob -20˚C Lub Freezer
Daim ntawv thov Cov cawv me me ntawm cov cawv, ze nrog kev txo cov ntshav lipid thiab kev txwv tsis pub platelet sib xyaw. Resveratrol yog qhov tshwj xeeb inhibitor ntawm COX-1, thiab nws tseem ua rau cov kev cuam tshuam hydroperoxidase ntawm COX-1. Nws tau pom tias inhibit cov xwm txheej cuam tshuam nrog cov qog pib, nce qib thiab nce zuj zus.
Kuaj Cov Ntaub Ntawv Qhov

 

Resveratrol General Cov Lus Qhia

Resveratrol yog ib hom kab mob antioxidant tshwm sim hauv cov txiv hma liab cov txiv ntoo. Resveratrol hmoov yog paub tias muaj ntau yam txiaj ntsig kev noj qab haus huv thiab cov txiaj ntsig nootropic. Resveratrol feem ntau yuav tsum mloog zoo feem ntau hauv cov tawv thiab cov noob ntawm cov txiv hmab thiab kua txiv ntoo. Cov seem ntawm cov txiv hmap muaj nyob hauv kev kho mob ntawm cov cawv txiv ntoo liab, yog li nws qhov tshwj xeeb tshaj yog tsom ntawm resveratrol.

Txawm li cas los xij, ntau ntawm kev tshawb fawb ntawm resveratrol tau ua tiav rau hauv cov tsiaj thiab kuaj cov tub ntxhais tub ntxhais siv cov khoom siv nyiaj ntau ntawm qhov sib txuas.

Ntawm qhov kev tshawb nrhiav tsawg tsawg hauv tib neeg, feem ntau tau tsom mus rau cov ntaub ntawv ntxiv ntawm cov compound, nyob rau hauv ntau ntau dua li cov uas koj tuaj yeem tau txais los ntawm cov khoom noj.

 

Resveratrol hmoov (501-36-0) Keeb kwm

Thawj qhov hais txog ntawm resveratrol yog nyob rau hauv lus Nyij Pooj xyoo 1939 los ntawm Michio Takaoka, uas cais nws los ntawm Veratrum album, ntau yam grandiflorum, thiab tom qab ntawd, xyoo 1963, los ntawm cov hauv paus ntawm Japanese knotweed.

 

Resveratrol Mechanism Ntawm Kev Ua

Resveratrol cuam tshuam nrog txhua peb theem ntawm carcinogenesis - kev pib, nce qib thiab vam meej. Kev sim nyob rau hauv kab lis kev cai ntawm ntau yam thiab cais tawm kev cais nyob rau hauv vitro cuam tshuam ntau cov txheej txheem hauv cov chaw ua haujlwm pharmacological ntawm resveratrol. Cov tswv yim no suav nrog kev hloov pauv ntawm qhov hloov pauv ntawm NF-kB, kev txwv tsis pub cytochrome P450 isoenzyme CYP1A1 (txawm hais tias qhov no yuav tsis cuam tshuam rau CYP1A1-mediated bioactivation ntawm procarcinogen benzo (a) pyrene), kev hloov pauv hauv androgenic kev ua thiab kev hais tawm thiab kev ua haujlwm ntawm cov pa roj carbon monoxide cyclooxygenase (COX).

Resveratrol tau tshaj tawm tias muaj txiaj ntsig tawm tsam neuronal cell ua haujlwm tsis zoo thiab tuag ntawm tes, thiab hauv kev tshawb xav tuaj yeem pab tiv thaiv cov kab mob xws li Huntington tus kab mob thiab Alzheimer tus kab mob. Ib zaug ntxiv, qhov no tseem tsis tau raug sim hauv tib neeg rau ib yam kab mob.

Kev tshawb fawb ntawm Northeastern Ohio Universities College ntawm cov tshuaj thiab Ohio State University qhia tias resveratrol muaj cov tshuaj tiv thaiv ncaj qha rau cov kev mob plawv thiab tej zaum yuav txwv tsis pub hloov kho lub plawv.

Nco ntsoov tias resveratrol bioavailability nyob ntawm nws cov ntawv conjugate: glucuronate thiab sulfonate, txawm hais tias feem ntau ntawm cov kev tshawb fawb hauv vitro siv aglycone daim ntawv ntawm resveratrol ('aglycone' txhais tau tias tsis muaj suab thaj molecule txuas, xws li hauv daim duab hauv tsab xov xwm no).

 

Resveratrol hmoov Daim Ntawv Thov

Resveratrol tuaj yeem tiv thaiv oxidation ntawm lipoprotein ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom ntom, thiab muaj peev xwm tiv thaiv kab mob plawv, mob qog noj ntshav, tiv thaiv kab mob thiab tiv thaiv kab mob. Nws lub luag haujlwm tseem ceeb yog antioxidant cov khoom.

Tshuaj mob plawv. Nws tuaj yeem txo cov roj hematic thiab tiv thaiv kab mob plawv. Nws tseem muaj cov nyhuv ntawm AIDS.

Antioxidants thiab cov haujlwm hauv kev tiv thaiv kab mob, antithrombotic, tiv thaiv mob qog noj ntshav, tshuaj tiv thaiv kab mob, anti hyperlipidemia thiab antibacterial.

Kev tiv thaiv kev laus, tswj ntshav lipid, tiv thaiv plawv plawv, tiv thaiv kab mob siab.

Resveratrol yog phytoalexin tsim tawm los ntawm ntau cov nroj tsuag nrog rau kev tiv thaiv qog, tiv thaiv mob, ntshav qab zib-txo qis thiab lwm cov txiaj ntsig txog hlab plawv.

 

Resveratrol (501-36-0) Kev tshawb fawb ntxiv

Raws li kev noj zaub mov ntxiv, noj 250mg ob zaug ib hnub, lossis qhia los ntawm koj tus kws kho mob. Nws raug nquahu kom noj nrog zaub mov txhawm rau kom lub cev nqus tau. Nws kuj yog qhov zoo tshaj plaws los coj nws nrog lwm cov txiv hmap extract lossis nrog txiv quav ntswv nyoos, vim tias qhov no ua rau cuam tshuam nrog Resveratrol ntau tshaj tawm. Ib teev milligram xav tau txhawm rau ntsuas qhov tseeb tshuaj.

 

Resveratrol hmoov (501-36-0) Kev siv

  • Timmers S., Konings E., Bilet L, li al. Calorie Kev Txwv-zoo li cuam tshuam ntawm 30 hnub ntawm Resveratrol Pab ntxiv rau ntawm Kev Zog Hluav Taws Xob thiab Kev Tshaj Tawm Metabolic nyob rau hauv tib neeg rog. Cell Kev Ntsuas Hlau 2011; 14: 612-622
  • Powell, RG, li al.: Phytochemistry, 35, 335 (1994), Jeandet, P., li al .: J. Phytopathol., 143, 135 (1995), Mattivi, F., li al .: J. Agric Cov. Khoom Noj Khoom Haus Chem., 43, 1820 (1995)
  • Leiro J, Arranz JA, Fraiz N, Sanmartín ML, Quezada E, Orallo F (2005). "Ntxim ntawm cis-resveratrol rau caj ces koom tes nrog qhov ua tau nuclear kappa B teeb liab". Rau cov menyuam. Immunopharmacol. 5 (2): 393–

 

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