Olivetol hmoov (500-66-3)

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Qeb: SKU: N / A

Lub npe: Olivetol (3,5-hydroxypentylbenzene)

CAS: 500-66-3

Cov roj formula: C11H16O2

KHOOM: Khaws rau hauv qhov chaw txias thiab qhuav. Khaws kom deb ntawm tshav ntuj ncaj qha thiab cua sov.

Olivetol hmoov (500-66-3) video

Olivetol hmoov (500-66-3) Cov Ntawv Qhia Hauv Paus

lub npe Olivetol (3,5-hydroxypentylbenzene) hmoov
CAS 500-66-3
purity 98%
Tshuaj lub npe Olivetol
Synonyms 3,5-Dihydroxyamylbenzene; 5-n-Amylresorcinol; 5-n-Pentylresorcinol; 1,3-Dihydroxy-5-pentylbenzene; 5-Pentyl-1,3-benzenediol;
molecular Formula C11H16O2
molecular Nyhav 180.2435
Melting Point 46-48 ° C (lit.)
InChI Qhov Tseem Ceeb IRMPFYJSHJGOPE-UHFFFAOYSA-N
daim ntawv khoom
tsos lub teeb paj yeeb rau xim av crystalline
Ib Sim Neej /
solubility Soluble hauv dej (qee qhov tsis paub meej), chloroform, thiab methanol.
cia mob Hauv cov tsev khaws khoom qhuav thiab cua tshuab; cia kom deb ntawm tshav ntuj; tsis txhob tua hluav taws; tsis txhob ya raws.
Daim ntawv thov Olivetol yog biosynthesized los ntawm polyketide synthase-hom tshuaj tiv thaiv los ntawm hexanoyl-CoA thiab peb lwg ntawm malonyl-CoA los ntawm aldol hws ntawm tetraketide nruab nrab.
Kuaj Cov Ntaub Ntawv Qhov

 

Olivetol hmoov (500-66-3) Cov Lus Qhia dav dav

Olivetol tau siv los ua cov qauv txheej txheem nyob rau hauv cov tshuaj hluavtaws cov tshuaj molecularly imprinted polymer (MIP). Nws kuj tau siv los ua lub zog ntawm (S) -mephenytoin 4′-hydroxylase kev ua si ntawm recombinant CYP2C19.

Olivetol siv ntau txoj hauv kev los tsim cov hluavtaws sib piv ntawm THC.full citation xav tau] Ib txoj kev no yog qhov hws tawm ntawm olivetol thiab pulegone. Hauv PiHKAL, Alexander Shulgin qhia txog kev ua cov txheej txheem tsim cov khoom qub los ntawm kev nqa cov tshuaj tiv thaiv olivetol thiab cov roj tseem ceeb ntawm cov txiv kab ntxwv thaum muaj phosphoryl chloride.

Ib txoj hauv kev rau cov hluavtaws ntawm THC nws tus kheej muaj qhov hws tawm ntawm olivetol thiab Δ2-carene oxide

 

Olivetol hmoov (500-66-3) Keeb Kwm

Olivetol yog biosynthesized los ntawm polyketide synthase-hom tshuaj tiv thaiv los ntawm hexanoyl-CoA thiab peb lwg ntawm malonyl-CoA los ntawm ib qho aldol hws ntawm tetraketide nruab nrab. Hauv 2009, Taura li al. tau clone ib hom III PKS lub npe hu ua olivetol synthase (OLS) los ntawm Cannabis sativa. Cov PKS no yog homodimeric protein uas muaj 385 amino acid polypeptide nrog cov roj molecular ntawm 42,585 Ntaj uas muaj qib zoo sib xws (60-70%) tus kheej los cog PKS's.

 

Olivetol hmoov (500-66-3) Daim Ntawv Thov

1, Siv los ua kws kev lag luam.

2, Siv Raws li Kev Nruab Nrab Organic.

3, Siv raws li kev txiav txim siab ntawm lipopolysaccharides, carrageenan thiab sialic acid.

 

Olivetol hmoov (500-66-3) Kev tshawb fawb ntxiv

Kev tsim, kev muaj, thiab / lossis kev faib tawm ntawm olivetol tsis raug cai los ntawm lub teb chaws twg; txawm li cas los xij, hauv tebchaws Meskas, nws yog DEA saib xyuas ua ntej.

 

Olivetol hmoov (500-66-3) Kev siv

  • Kumano, T., li al .: Bioorg. Med. Chem., 16, 8117 (2008), Appendino, G., li al.: J. Nat. Prod., 71, 1427 (2008), Sampietro, D., li al .: Khoom Noj Chem., 115, 1170 (2009),
  • Cov. Jiang R, li al. Cannabidiol yog lub zog txwv rau ntawm kev ua catalytic ntawm cytochrome P450 2C19. Yeeb Tshuaj Metab Pharmacokinet. 2013; 28 (4): 332-8.
  • Cov. Yamaori S, li al. Cannabidiol, ib qho loj phytocannabinoid, raws li lub zog atypical inhibitor rau CYP2D6. Tshuaj Mob Cawv Lub Cev. 2011 Nov; 39 (11): 2049-56.

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