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HBT1 Hmoov (489408-02-8)

HBT1 hmoov yog ib qho AMPA-R [alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptor] hwj chim uas tsim cov khoom tawm ntawm lub hlwb los ntawm neurotrophic factor (BDNF) thawj neurons. HBT1 khi rau ligand-binding domain ntawm AMPA-R hauv glutamate dependant yam.

Chaw Tsim Tshuaj: Batch Production
pob: 1KG / hnab, 25KG / nruas
Wisepowder muaj peev xwm tsim tau thiab muab khoom ntau. Txhua qhov kev tsim khoom raws li cGMP thiab kev tswj hwm nruj, tag nrho cov ntaub ntawv xeem thiab cov qauv muaj.
Qeb:

HBT1 Hmoov (489408-02-8) video

 

HBT1 Hmoov (489408-02-8) Cov Lus Qhia Hauv Zej Zog

lub npe HBT1 hmoov
CAS 489408-02-8
purity 98%
Tshuaj lub npe 2-(((5-Methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)acetyl)amino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
Synonyms HBT1; HBT-1; HLB 1
molecular Formula C16H17F3N4O2S
molecular Nyhav 386.39
Melting Point /
InChI Qhov Tseem Ceeb PHLXSNIEQIKENK-UHFFFAOYSA-N
daim ntawv hmoov
tsos dawb mus rau beige
Ib Sim Neej /
solubility DMSO: 2 mg / mL, ntshiab
cia mob 0 - 4 C rau lub sij hawm luv (hnub rau lis piam), lossis -20 C rau lub sij hawm ntev (hli).
Daim ntawv thov AMPA receptor hwj chim
Kuaj Cov Ntaub Ntawv Qhov

 

HBT1 Hmoov (489408-02-8) Cov Lus Qhia dav dav

HBT1 hmoov yog AMPA receptor potentiator nrog qis dua kev ua phem, zam lub tswb zoo li teb hauv vitro BDNF ntau lawm. Nws yog AMPA-R [alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptor] hwj chim uas tsim cov khoom tawm ntawm lub hlwb los ntawm neurotrophic (BDNF) thiab nthuav tawm me ntsis kev cuam tshuam hauv thawj neurons. HBT1 khi rau ligand-binding domain ntawm AMPA-R hauv glutamate dependant yam.

 

HBT1 Hmoov (489408-02-8) Kev siv

[1] Kunugi A, Tajima Y, Kuno H, Sogabe S, Kimura H. HBT1, Tus Tshiab AMPA Receptor Potentiator nrog qis Agonistic nyhuv, Avoided Tsaj-Cov Lus Teb nyob rau hauv Vitro BDNF ntau lawm. J Pharmacol Exp Ther. 2018 Mar; 364 (3): 377-389. doi: 10.1124 / jpet.117.245050. Epub 2018 Jan 3. PubMed PMID: 29298820.
 

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