cov khoom siv

pinoline hmoov (20315-68-8)

Pinoline hmoov yog methoxylated tryptoline (5-methoxytryptoline) ntev tau lees tias yuav tsim tawm hauv lub caj pas pineal thaum lub cev metabolism ntawm melatonin, txawm li cas los xij nws qhov teeb meem pineal tseem muaj kev sib cav. Nws lub npe IUPAC yog 6-methoxy-1,2,3,4-tetrahydro-bol-carboline, feem ntau sau ua 6-MeO-THBC, thiab nws lub npe muaj ntau yog ua ke ntawm "pineal beta-carboline". Cov kev ua lom neeg hauv cov qauv no tau muaj kev txaus siab ua qhov muaj peev xwm pub dawb radical scavenger, tseem hu ua antioxidant, thiab raws li monoamine oxidase A inhibitor.

Chaw Tsim Tshuaj: Batch Production
pob: 1KG / hnab, 25KG / nruas
Wisepowder muaj peev xwm tsim tau thiab muab khoom ntau. Txhua qhov kev tsim khoom raws li cGMP thiab kev tswj hwm nruj, tag nrho cov ntaub ntawv xeem thiab cov qauv muaj.

pinoline hmoov (20315-68-8) video

 

pinoline hmoov (20315-68-8) Cov Ntaub Ntawv Hauv Paus

lub npe pinoline hmoov
CAS 20315-68-8
purity 98%
Tshuaj lub npe 6-Methoxy-1,2,3,4-tetrahydro-9H-pyrido [3,4-b] indole
Synonyms 20315-68-8

6-methoxy-2,3,4,9-tetrahydro-1H-pyrido [3,4-b] indole

6-methoxytryptoline

6-Methoxy-1,2,3,4-tetrahydro-beta-carboline

xov tooj liab

molecular Formula C12H14N2O
molecular Nyhav 202.257 g / mol
Melting Point 216- 224 ° C
InChI Qhov Tseem Ceeb QYMDEOQLJUUNOF-UHFFFAOYSA-N
daim ntawv Khoom
tsos
Ib Sim Neej
solubility
cia mob
Daim ntawv thov Pinoline yog methoxylated tryptoline (5-methoxytryptoline) ntev tau lees tias yuav tsim tawm hauv lub caj pas pineal thaum lub cev metabolism ntawm melatonin,
Kuaj Cov Ntaub Ntawv Qhov

 

pinoline hmoov General Cov Lus Qhia

Pinoline (6-methoxy-tetrahydro-beta-carboline) hmoov tuaj yeem tsim nyob rau hauv lub cev mammalian nyob rau hauv kev mob tshwm sim los ntawm 5-hydroxytryptamine los yog raws li tricyclic metabolite ntawm melatonin. Ob lub melatonin thiab pinoline inhibited lipid peroxidation thiab qhia cov kev ua haujlwm zoo sib xws hauv kev ntsuas tag nrho antioxidant xwm txheej. Cov txiaj ntsig no txhawb qhov tseem ceeb ntawm indolic ib feem ntawm molecule thiab pawg 5-methoxy ntau rau ob lub tebchaw raws li qhov muaj peev xwm ntawm cov lwg me me no los txiav tawm hydroxyl radicals.

 

pinoline (20315-68-8) Kev tshawb fawb ntxiv

Raws li pinoline tau pom los ua kom muaj cov tshuaj tiv thaiv zoo li cov nyhuv hauv kev sim coj tus cwj pwm thiab tau tshaj tawm tias muaj tshuaj lom tsawg, qhov sib xyaw no yuav tsum tau kawm ntxiv raws li muaj peev xwm tiv thaiv kev nyuaj siab nrog hais tawm cov teebmeem antioxidative. Cov txiaj ntsig no txuas ntxiv txhawb qhov tseem ceeb ntawm caj pas pineal hauv kev tiv thaiv kev tiv thaiv kab mob.

 

pinoline (20315-68-8) Kev siv

  1. Schiller, Erich; Bartsch, H. (2003). Free Radicals thiab Inhalation Pathology: Lub Txheeb Xyuas Lub Zog, Mononuclear Phagocyte System, Hypoxia thiab Reoxygenation, Pneumoconioses, thiab Lwm Granulomatoses, Cancer (Google Cov Ntawv, nplooj ntawv saib). Caij nplooj ntoos hlav. p. 107. ISBN 978-3-540-00201-7. Txais Xyoo 2009-02-14.
  2.  Airaksinen, MM, Huang, JT, Ho, BT, Taylor, D., thiab Walker, K. (1978). "Qhov tseeb ntawm 6-Methoxy-1,2,3,4-Tetrahydro-bol-carboline thiab nws cov nyhuv ntawm 5-Hydroxytryptamine Uptake thiab Tso Tawm Hauv Cov Ntshav Ntshav". Acta Cov Tshuaj Pharmacol Toxicol. 43 (5): 375–380. doi: 10.1111 / j.1600-0773.1978.tb02281.x.
  3. Bartels, SP (2006) Asmeskas Patent No. 20,060,292,202 Washington, DC: Asmeskas
  4. {Mario de la Fuente li al. 2015 "Neurogenic Kev Ntsuam Xyuas Muaj Peev Xwm thiab Pharmacological cov yam ntxwv ntawm 6-Methoxy-1,2,3,4-tetrahydro-bol-carboline (Pinoline) thiab Melatonin – Pinoline Hybrids" http://pubs.acs.org/doi/abs/10.1021 /acschemneuro.5b00041}

 

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