Hydrafinil (9-Fluorenol) hmoov (1689-64-1)

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5-10 teev (hauv hnub ua haujlwm) ceev shipping
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Tsuas yog 13 sab lauj! 76 tus neeg tab tom saib qhov no thiab 64 tus neeg muaj nws hauv lawv lub laub.

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[1]. Xaiv qhov koj xav tau, tom qab ntawd ntxiv rau lub laub

[2]. Txuas mus xyuas

[3]. Sau koj cov ntaub ntawv nthuav dav, qhov * yuav tsum tau, xaiv koj txoj kev them nyiaj. Muaj ntau txoj kev them nyiaj sib txawv suav nrog:
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Lub tswv yim: email chaw nyob yuav tsum tau kho, cov ntaub ntawv taug qab yuav hloov tshiab los ntawm email ceeb toom

[4]. Yog tias xaiv "Coinpayment", tom qab nyem "Place order", ces yuav qhia raws li hauv qab no them

[5]. Yog tias Xaiv "Direct Bank Transfer", tom qab nias "Place order", ces yuav qhia raws li hauv qab no, yuav tshwm sim cov ntsiab lus ntawm tus account hauv txhab nyiaj, tom qab hloov lub txhab nyiaj (thov siv koj tus lej xaj raws li qhov siv), xa daim ntawv hauv txhab nyiaj rau peb.

[6]. Kev them nyiaj lees paub
[7]. Parcel xa tawm li 5-10 teev (hauv hnub ua haujlwm)
[8]. Tus lej taug qab tau muab
[9]. Parcel tuaj txog
[10]. Rov xaj dua
Tsis muaj koj qhov ntau? Nyem no
Ceeb toom: Yog tias koj cev xeeb tub, saib xyuas neeg mob, noj cov tshuaj los yog muaj kev mob nkeeg nrog koj tus kws kho mob ua ntej siv. Khaws kom deb ntawm cov menyuam yaus.
Qeb: SKU: N / A

Lub npe: Hydrafinil

CAS: 1689-64-1

Cov mis mos molecular: C13H10O

KHOOM: Khaws rau hauv qhov chaw txias thiab qhuav. Khaws kom deb ntawm tshav ntuj ncaj qha thiab cua sov.

Hydrafinil (9-Fluorenol) hmoov (1689-64-1) video

 

Cov Ntaub Ntawv Hydrafinil (9-Fluorenol) Cov Ntaub Ntawv Hauv Paus

lub npe Hydrafinil (9-Fluorenol) hmoov
CAS 1689-64-1
purity 98%
Tshuaj lub npe hydrafinil;Hydranafil;9-FLUORENOL;fluoren-9-ol;Hydroxyfluoren;9h-fluoren-9-ol;Fluoren-9-ol 97%;9-HYDROXYFLUORENE;9-HYDROXY-FLUOREN;9-Fluorenol, 98+%
Synonyms 9-Hydroxy fluorene
molecular Formula C13H10O
molecular Nyhav 182.22 g / mol
Melting Point 152-155 ° C
InChI Qhov Tseem Ceeb AFMVESZOYKHDBJ-UHFFFAOYSA-N
daim ntawv Khoom
tsos Cov xim dawb-crystalline
Ib Sim Neej 6 rau 8 teev
solubility Chloroform (Tsawg), Methanol (Me Nyuam)
cia mob tub yees
Daim ntawv thov Siv tshuaj, khoom noj khoom haus, khoom noj, dej haus, tshuaj pleev ib ce, tshuaj lom thiab tshuaj reagents thiab lwm yam lag luam.
Kuaj Cov Ntaub Ntawv Qhov

 

Hydrafinil (9-Fluorenol) Cov Lus Qhia dav dav

Hydrafinil (9-Fluorenol) hmoov yog cawv tso tawm los ntawm fluorene. Hauv qhov tseem ceeb isomer, fluoren-9-ol lossis 9-hydroxyfluorene, pawg hydroxy nyob rau ntawm cov roj carbon nruab nrab ntawm ob lub nplhaib benzene. Hydroxy fluorene tuaj yeem hloov mus rau Hydrafinil (9-Fluorenol) los ntawm kev tiv thaiv oxidation. Nws yog cov xim dawb-xim dawb nyob hauv chav sov.

Hydrafinil (9-Fluorenol) hmoov yog cawv tso tawm ntawm fluorene thiab raug ua ib qhov kev lom zem zoo li eugeroic compound, txhawb kev muaj peev xwm sawv. Lub tuam txhab Cephalon soj ntsuam Hydrafinil (9-Fluorenol) hauv kev sib piv rau cov tshuaj nrov eugeroic modafinil. Hauv lawv cov kev tshawb fawb sib piv nrog cov nas, lawv tau sau tseg tias Hydrafinil (9-Fluorenol) muaj txiaj ntsig zoo dua li modafinil (nce txog 39%). Txawm hais tias nws muaj dopamine reuptake cov khoom, lawv zoo li yuav tsis muaj zog.

 

Hydrafinil (9-Fluorenol) hmoov Keeb Kwm

Hydrafinil (9-Fluorenol) hmoov yog ib qho kev tshawb fawb tsis raug tswj hwm tshuaj lom neeg thaum xub thawj los ntawm Cephalon Pharmaceuticals (tam sim no muaj los ntawm Teva) ua eugeroic (wakefulness-txhawb tus neeg sawv cev). Tom qab nws cov tshuaj synthester, Hydrafinil (9-Fluorenol) yog ib tus ntawm ntau tus neeg sawv cev uas pom tau tias yog qhov kev cia siab rau qhov kev vam meej rau cov tshuaj muaj npe thiab FDA pom zoo, Provigil (Modafinil). Cov ntaub ntawv sib piv los ntawm cov tsiaj sim pom tias Hydrafinil (9-Fluorenol) nthuav tawm ~ 39% ntau dua kev siv eugeroic ntau dua li modafinil nyob rau lub sijhawm luv (4 teev).

Txawm li cas los xij, rau qhov laj thawj tsis meej, Cephalon tshem tawm Hydrafinil (9-Fluorenol) yog qhov muaj peev xwm tshiab tshiab eugeroic. Hloov chaw, lawv tau taw qhia cov kev siv zog thiab cov peev txheej los tshawb xyuas, tsim kho, thiab ua lag luam tshuaj armodafinil. Armodafinil (muag nyob rau hauv lub npe lag luam "Nuvigil") yuav dhau los ua cov kws tshaj lij tus kws tshaj lij tshuaj mus rau Provigil, ua rau ntau tus xav tias Hydrafinil (9-Fluorenol) tej zaum yuav muaj kev loj hlob zoo dua.

Qee qhov xav tias Hydrafinil (9-Fluorenol) cov kev siv yav dhau los ua cov tshuaj tua kab hauv xyoo 1930, ua pov thawj muaj tshuaj lom rau cov tsiaj muaj tsiaj, thiab kev siv lub caij nyoog Cephalon patent yuav muaj laj thawj txaus los txiav tawm nws txoj kev txhim kho. Raws li ntawm 2015, Hydrafinil (9-Fluorenol) tau rov qab muaj koob npe ntawm cov neeg nyiam nootropic thiab tam sim no raug muag ua ib yam tshuaj nyob hauv internet tsis muaj npe tswj hwm hauv qab hom "Hydrafinil." Coob tus neeg tus kheej tau sim kho kom nws tau txais txiaj ntsig, tab sis lwm tus neeg tsis ntseeg txog cov kev thov no thiab xav tsis thoob ntawm nws qhov tsis muaj ntaub ntawv pov thawj, qhov muaj feem ua rau muaj kev phom sij.

 

Hydrafinil (9-Fluorenol) Kev Siv Tes Haujlwm Ntawm Kev Ua

Lub tshuab ntawm kev nqis tes ua nrog hydrafinil yog qhov tsis meej. Ntau tus xav hais tias nws ua haujlwm li 5-HT6 receptor antagonist thiab tsis yoog raws dopamine reuptake inhibitor (DRI). Txawm hais tias cov kev xav tau no muaj tseeb los yog kev sib cav vim tias nws tsis tau tshawb fawb tawm hauv tib neeg. Hauv kev hais txog, hydrafinil yuav bolsters psychomotor vigilance thiab lub peev xwm kev ua tau zoo tus thawj coj ntawm upregulation ntawm dopaminergic thiab noradrenergic kis.

 

Hydrafinil (9-Fluorenol) Daim Ntawv Thov

9-Fluorenol tseem tseem hu ua hydrafinil thiab yog lub cim xeeb txuas ntxiv ntawm kev txawj ntse ua kom pom tau tias 39% zoo dua li modafinil hauv kev tswj kev ua kom paub qab hau. Nws yog 140% ua kom tau txiaj ntsig zoo li modafinil ntawm kev txhawb nqa los ntawm kev tsim tsa thiab tsis muaj kev cuam tshuam zoo ib yam li modafinil. Nws kuj tsis nyob ntev li ntev, ua rau nws yooj yim dua rau koob tshuaj ntau dua, tsis tas tos 12 teev ntawm cov teebmeem

Hydrafinil (9-fluorenol) tsis raug ntxiv

Hydrafinil (9-Fluorenol) belongs rau ib chav kawm ntawm cov tshuaj hu ua Eugeroics. Cov no yog cov tshuaj tiv thaiv uas tsim tawm lub siab lub ntsws ntev ntev uas ua rau kev tsim lub siab. Lub tswv yim tom qab tsim tawm ntawm cov tshuaj no yog txhawm rau txhim kho neeg lub cev tsis tas yuav ua kom pom qhov teebmeem ntawm lub cev los yog zoo dua qub kev tsim txom / zam rau / quav ntawm cov tshuaj muaj peev xwm. Thiab Hydrafinil (9-Fluorenol) tsis txawv.

Hydrafinil kev txhawb nqa ntawm dopamine txoj hauv kev yog qhov tsis tshua muaj txiaj ntsig ntau dua li modafinil's uas txhais tau hais tias nws yog qhov tsawg feem ntau yuav muaj yees.

Hydrafinil (9-fluorenol) tsis yog carcinogenic thiab lom rau tib neeg

Cov tshuaj no yog cawv cawv los ntawm fluorine. Nws hydroxyl pawg yog tso ntawm nws ob lub benzene rings ntawm tus choj txuas. Cov txheej txheem oxidation tuaj yeem siv los hloov cov hydroxyfluorene rau fluorenone. Cov compound no tsis yog cov kabmob tua kabmob lossis tsis yog lom rau tib neeg. Yog li, txoj kev tshawb no tau ua los ntawm Chemists ua haujlwm rau Cephalon (lub tuam txhab bio-kws tshuaj), tau pom zoo nrog cov tshuaj uas yuav ua tiav Modafinil, tshuaj los tiv thaiv narcolepsy.

Nws kuj tsis nyob ntev li ntev, ua rau nws yooj yim dua rau koob tshuaj ntau dua, tsis tas tos 12 teev ntawm cov teebmeem. Nws tau qis me ntsis DAT affinities tab sis muaj ntau dua eugeroic kev ua. Nws muaj zog ntau dua li modafinil nrog 50-100mg sib haum rau 100-200mg rau modafinil. Nws qhia tau tias tsis muaj tshuaj lom thiab tsis muaj mob siab.

 

Hydrafinil (9-Fluorenol) Kev tshawb fawb ntxiv

Hydrafinil (9-Fluorenol) muaj tshuaj lom rau cov tsiaj hauv lub cev nrog rau algae, kab mob, thiab crustaceans. Hydrafinil (9-Fluorenol) tau ua daim ntawv tso cai ua tus tshuaj tua kab hauv xyoo 1939, thiab yog ib qho algaecide tiv thaiv ntsuab algae Dunaliella bioculata.

Nws cov kuab lom thiab carcinogenicity hauv tib neeg tsis paub.

Kev tshawb fawb luam tawm los ntawm cov kws tshuaj ua haujlwm rau biopharmaceutical tuam txhab Cephalon los tsim kev ua tiav ntawm cov txheej txheem eugeroic modafinil tau tshaj tawm tias sib luag Hydrafinil (9-Fluorenol) derivative tau 39% zoo dua li modafinil ntawm kev ua kom cov nas tsaug zog nyob rau 4-teev. Nws yog qhov ua kom tsis muaj zog dopamine reuptake inhibitor nrog IC50 ntawm 9 59M, tshwj xeeb yog 50% tsis muaj zog dua li modafinil (IC3.70 = 450 μM) txawm hais tias ua ib qho muaj zog eugeroic, muaj peev xwm ua rau nws tsis tshua lav rau qhov quav. Nws kuj pom tias tsis muaj kev sib raug zoo rau cytochrome P2 19CXNUMX, tsis zoo li modafinil.

 

Hydrafinil (9-Fluorenol) Kev Siv Khoom Siv

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