Coluracetam hmoov (135463-81-9)

Coluracetam hmoov (135463-81-9) video

Coluracetam hmoov Piav Cov Ntaub Ntawv

Coluracetam hmoov General Cov lus piav qhia

Coluracetam hmoov, nrog CAS 135463-81-9, tseem hu ua BCI-540 thiab MKC-231. Coluracetam tau tsim nyob rau hauv Nyij Pooj thiab tsuas yog sau npe hauv xyoo 2005 los ntawm Mitsubishi Tanabe Pharmaceutical Corporation, thiab tom qab ntawd nws daim ntawv cog lus tau hloov mus rau BrainCells Inc.

Coluracetam hmoov yog lub hlwb ntxiv rau kev txhim kho kev txawj ntse, txhim kho kev nco qab zoo li tseem kho kho Cov Mob Loj Mob Nyuaj Siab (MDD) thiab tseem muaj teeb meem kev ntxhov siab.

Coluracetam hmoov (135463-81-9) Keeb Kwm

Coluracetam (INN) (tus lej npe BCI-540; yav tas los MKC-231) hmoov yog tus neeg sawv cev ntawm cov racetam tsev neeg. Nws tau pib tsim thiab sim los ntawm Mitsubishi Tanabe Pharma Corporation rau Alzheimer tus kab mob. Tom qab cov tshuaj tsis ua tiav rau kev xaus rau nws cov kev sim tshuaj kho mob nws tau raug tso cai los ntawm BrainCells Inc rau kev tshawb xyuas rau qhov kev tsis txaus siab loj (MDD), uas tau dhau los ua ntej tau txais txiaj ntsig "Tsim Kho Kev Tshawb Fawb Kev Tshawb Nrhiav Qhov Peev" los ntawm lub xeev California.

Kev tshawb pom los ntawm ntu IIa kev soj ntsuam tau qhia tau tias nws yuav yog ib qho tshuaj kho mob rau comorbid MDD nrog cov kev nyuaj siab dav dav (GAD). BrainCells Inc yog tam sim no [thaum?] Tawm-tso cai cov tshuaj rau lub hom phiaj no. [Tag nrho hais txog kev xav tau] Nws kuj tseem yuav muaj peev xwm siv kev tiv thaiv thiab kho ischemic retinopathy thiab kev mob hlwb thiab rov qab thiab kho qhov muag.

Coluracetam tau pom tias yuav thim rov qab qhov kev poob qis ntawm choline acetyltransferase ntau lawm hauv cov kab mob nruab nrab hauv cov nas los ntawm phencyclidine (PCP), thiab suav hais tias yog qhov muaj peev xwm kho tshuaj rau schizophrenia.

Coluracetam (135463-81-9) Lub Tswv Yim Ntawm Kev Ua

Coluracetam txhim kho kev sib raug zoo choline nqus (HACU), uas yog tus lej-txwv theem ntawm acetylcholine (ACh) kev sib xyaw. Cov kev tshawb fawb tau qhia coluracetam rau txhim kho kev kawm tsis tau ntawm ib qho tshuaj qhov ncauj muab rau nas uas tau kis rau cholinergic neurotoxins. Cov kev tshawb fawb tom ntej no tau qhia tias nws tuaj yeem ua rau muaj kev cuam tshuam txog kev paub ntev hauv cholinergic neurotoxin-kho cov nas los ntawm kev hloov pauv choline txoj cai tswj hwm.

Cov txiaj ntsig ntawm Coluracetam (135463-81-9)

Coluracetam yog ib qho nootropic sib txuas hauv cov tsev neeg racetam, nrog qhov tshwj xeeb txhim kho cov nyhuv ntawm qhov muaj siab choline uptake.
Coluracetam tuaj yeem ua tau txhim kho kev nco, kev kawm, kev ntxhov siab, kev nyuaj siab, thiab qhov muag. Nws muaj peev xwm siv tau hauv kev tiv thaiv thiab kho mob ischemic retinopathy thiab retinal thiab optic paj hlwb raug mob. Nws kuj tseem tuaj yeem txhim kho kev kawm tsis tau ntawm ib koob tshuaj ib zaug rau cov nas uas tau kis rau cholinergic neurotoxins.
Nws yuav ua rau lub siab ntev ua rau muaj qhov cuam tshuam hauv cholinergic neurotoxin-kho cov nas los ntawm kev hloov choline transporter txoj kev cai. Coluracetam tseem tau ua kom pom los txhim kho AMPA potentiation, uas yog tus txheej txheem uas ua rau muaj kev cuam tshuam ntawm kev txawj ntse thiab lub cev.

Coluracetam (135463-81-9) kev mob tshwm sim

Ib qho ntxiv, tus qauv racetam sab kuj tseem siv rau cov neeg siv ntawm Coluracetam. Qee cov neeg muaj kev tawm tsam nrog mob taub hau vim tsis muaj acetylcholine (raug kho los ntawm alpha GPC lossis citicoline). Lwm tus neeg muaj Colurracetam phiv xws li overstimulation lossis jitteriness, xeev siab, lossis txob taus.

Coluracetam (135463-81-9) Kev siv

• Takashina K, Bessho T, Mori R, Kawai K, Eguchi J, Saito K. MKC-231, choline uptake txhim kho: (3) Hom kev nqis tes ua ntawm MKC-231 hauv kev txhim kho qhov muaj txiaj ntsig choline uptake. J Neural Transm (Vienna). 2008 Jul; 115 (7): 1037. doi: 46 / s10.1007-00702-008-0049. PubMed PMID: 0.
• Bessho T, Takashina K, Eguchi J, Komatsu T, Saito K. MKC-231, choline-uptake txhim kho: (1) kev txhim kho kom paub txog kev txhim kho ntev tom qab kev coj ua hauv AF64A-kho cov nas. J Neural Transm (Vienna). 2008 Jul; 115 (7): 1019-25. doi: 10.1007 / s00702-008-0053-4. PubMed PMID: 18461272.
• Takashina K, Bessho T, Mori R, Eguchi J, Saito K. MKC-231, choline tuaj yeem txhim kho: (2) Cuam Tshuam thiab tso cov tshuaj acetylcholine hauv AF64A-kho cov nas. J Neural Transm (Vienna). 2008 Jul; 115 (7): 1027-35. doi: 10.1007 / s00702-008-0048-1. PubMed PMID: 18446264.
• Shirayama Y, Yamamoto A, Nishimura T, Katayama S, Kawahara R. Tom qab kis tau tus choline uptake enhancer MKC-231 antagonizes phencyclidine-induced tus cwj pwm tsis txaus thiab txo qis hauv septal cholinergic neurons hauv nas. Eur Neuropsychopharmacol. 2007 Sep; 17 (9): 616-26. PubMed PMID: 17467960.
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